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Defa-rs12 Gene Detail
Summary
  • Symbol
    Defa-rs12
  • Name
    defensin, alpha, related sequence 12
  • Synonyms
    Defcr-rs12
  • Feature Type
    protein coding gene
  • IDs
    MGI:102514
    NCBI Gene: 13221
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 8, Syntenic
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DEFA1, defensin alpha 1
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DEFA1, defensin alpha 1
  • Synonyms
    DEF1, DEFA2, HNP-1, HP-1, HP1, MRS
  • Links
    NCBI Gene ID: 1667
    neXtProt AC: NX_P59665
    UniProt: P59665

  • Chr Location
    8p23.1; chr8:6977649-6980092 (-)  GRCh38
  • Human Ortholog
    DEFA1B, defensin alpha 1B
  • Synonyms
    HNP-1, HP-1, HP1
  • Links
    NCBI Gene ID: 728358
    neXtProt AC: NX_P59665
    UniProt: P59665

  • Chr Location
    8p23.1; chr8:6996766-6999198 (-)  GRCh38
  • Human Ortholog
    DEFA3, defensin alpha 3
  • Synonyms
    DEF3, HNP-3, HNP3, HP-3, HP3
  • Links
    NCBI Gene ID: 1668
    neXtProt AC: NX_P59666
    UniProt: P59666

  • Chr Location
    8p23.1; chr8:7015869-7018297 (-)  GRCh38
  • Human Ortholog
    DEFA5, defensin alpha 5
  • Synonyms
    DEF5, HD-5
  • Links
    NCBI Gene ID: 1670
    neXtProt AC: NX_Q01523
    UniProt: Q01523

  • Chr Location
    8p23.1; chr8:7055304-7056739 (-)  GRCh38
  • Human Ortholog
    DEFA6, defensin alpha 6
  • Synonyms
    DEF6, HD-6
  • Links
    NCBI Gene ID: 1671
    neXtProt AC: NX_Q01524
    UniProt: Q01524

  • Chr Location
    8p23.1; chr8:6924697-6926076 (-)  GRCh38
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    20
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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  • Other Mouse Links
    GEO
Sequences &
Gene Models
less
  • All Sequences
    6
  • RefSeq
    2
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic U12566 GenBank | ENA | DDBJ | MGI Sequence Detail 1055 129 ±  kb
transcript NM_007846 RefSeq | MGI Sequence Detail 279 129  
polypeptide P50716 UniProt | EBI | MGI Sequence Detail 91 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 1
    Genomic 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-19352
References
more
  • Summaries
    All 11
    Gene Ontology 4
  • Earliest
    J:21466 Huttner KM, et al., A family of defensin-like genes codes for diverse cysteine-rich peptides in mouse Paneth cells. Genomics. 1994 Nov 1;24(1):99-109
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory