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Rdh11 Gene Detail
Summary
  • Symbol
    Rdh11
  • Name
    retinol dehydrogenase 11
  • Synonyms
    2610319N22Rik, Arsdr1, M42C60, Mdt1, Psdr1
  • Feature Type
    protein coding gene
  • IDs
    MGI:102581
    NCBI Gene: 17252
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:79221007-79238629 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 35.51 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    573 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_102581
 protein coding gene Chr12:79221007-79239067 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019881
 protein coding gene Chr12:79454522-79474836 (-)
A/J MGP_AJ_G0019839
 protein coding gene Chr12:76599918-76618735 (-)
AKR/J MGP_AKRJ_G0019814
 protein coding gene Chr12:78672835-78690689 (-)
BALB/cJ MGP_BALBcJ_G0019818
 protein coding gene Chr12:76853803-76872031 (-)
C3H/HeJ MGP_C3HHeJ_G0019624
 protein coding gene Chr12:79151123-79170060 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020270
 protein coding gene Chr12:81803575-81823225 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017889
 protein coding gene Chr12:73616008-73634799 (-)
CAST/EiJ MGP_CASTEiJ_G0019174
 protein coding gene Chr12:73982262-74001474 (-)
CBA/J MGP_CBAJ_G0019595
 protein coding gene Chr12:84997970-85017216 (-)
DBA/2J MGP_DBA2J_G0019710
 protein coding gene Chr12:76222861-76241376 (-)
FVB/NJ MGP_FVBNJ_G0019696
 protein coding gene Chr12:75035675-75053544 (-)
LP/J MGP_LPJ_G0019782
 protein coding gene Chr12:79389656-79408110 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019735
 protein coding gene Chr12:88035002-88053043 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020305
 protein coding gene Chr12:78190422-78211680 (-)
PWK/PhJ MGP_PWKPhJ_G0018940
 protein coding gene Chr12:70582806-70601821 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018734
 protein coding gene Chr12:72692429-72710349 (-)
WSB/EiJ MGP_WSBEiJ_G0019227
 protein coding gene Chr12:78807871-78828824 (-)



Homology
more
  • Human Ortholog
    RDH11, retinol dehydrogenase 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RDH11, retinol dehydrogenase 11
  • Synonyms
    ARSDR1, CGI82, HCBP12, MDT1, PSDR1, RALR1, RDJCSS, SCALD, SDR7C1
  • Links
    NCBI Gene ID: 51109
    neXtProt AC: NX_Q8TC12
    UniProt: Q8TC12

  • Chr Location
    14q24.1; chr14:67676800-67695793 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene exhibit delayed dark adaptation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    873
  • Tissues
    141
  • cDNA Data
    104
  • Literature Summary
    7
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 17252 NCBI Gene Model | MGI Sequence Detail 17623 C57BL/6J ±  kb
    transcript NM_001362269 RefSeq | MGI Sequence Detail 2991 ZRU/MplStud  
    polypeptide Q9QYF1 UniProt | EBI | MGI Sequence Detail 316 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 107
      cDNA 104
      Primer pair 2
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-19467, MGI:1914425, MGI:2144817, MGI:2144969, MGI:2145121
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 7
      Gene Ontology 8
      Phenotypes 15
    • Earliest
      J:19094 Hara T, et al., Characterization of cell phenotype by a novel cDNA library subtraction system: expression of CD8 alpha in a mast cell-derived interleukin-4-dependent cell line. Blood. 1994 Jul 1;84(1):189-99
    • Latest
      J:348785 Zhang D, et al., Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos. J Cell Physiol. 2024 Mar 26;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/29/2024
    MGI 6.24     		The Jackson Laboratory