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Fdx1 Gene Detail
Summary
  • Symbol
    Fdx1
  • Name
    ferredoxin 1
  • Synonyms
    ADRENODOXIN
  • Feature Type
    protein coding gene
  • IDs
    MGI:103224
    NCBI Gene: 14148
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:51854606-51874856 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 28.62 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    477 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103224
 protein coding gene Chr9:51854323-51874902 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034803
 protein coding gene Chr9:50902943-50923177 (-)
A/J MGP_AJ_G0034784
 protein coding gene Chr9:49326772-49347006 (-)
AKR/J MGP_AKRJ_G0034712
 protein coding gene Chr9:50371939-50392154 (-)
BALB/cJ MGP_BALBcJ_G0034776
 protein coding gene Chr9:49083766-49104000 (-)
C3H/HeJ MGP_C3HHeJ_G0034486
 protein coding gene Chr9:50868194-50888428 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035295
 protein coding gene Chr9:52325171-52345382 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032208
 protein coding gene Chr9:48770337-48792215 (-)
CAST/EiJ MGP_CASTEiJ_G0033808
 protein coding gene Chr9:50831121-50851315 (-)
CBA/J MGP_CBAJ_G0034457
 protein coding gene Chr9:54149384-54169591 (-)
DBA/2J MGP_DBA2J_G0034616
 protein coding gene Chr9:49186661-49206895 (-)
FVB/NJ MGP_FVBNJ_G0034558
 protein coding gene Chr9:48401937-48422311 (-)
LP/J MGP_LPJ_G0034698
 protein coding gene Chr9:51241478-51263955 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034601
 protein coding gene Chr9:55736985-55757219 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035317
 protein coding gene Chr9:50370692-50390911 (-)
PWK/PhJ MGP_PWKPhJ_G0033512
 protein coding gene Chr9:49174002-49196865 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033348
 protein coding gene Chr9:50642368-50666182 (-)
WSB/EiJ MGP_WSBEiJ_G0033920
 protein coding gene Chr9:50366710-50386945 (-)



Homology
more
  • Human Ortholog
    FDX1, ferredoxin 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FDX1, ferredoxin 1
  • Synonyms
    ADX, FDX, LOH11CR1D
  • Links
    NCBI Gene ID: 2230
    neXtProt AC: NX_P10109
    UniProt: P10109

  • Chr Location
    11q22.3; chr11:110429331-110464884 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    7
  • cDNA Data
    9
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032051 Ensembl Gene Model | MGI Sequence Detail 20251 C57BL/6J ±  kb
    transcript ENSMUST00000034552 Ensembl | MGI Sequence Detail 875 Not Applicable  
    polypeptide ENSMUSP00000034552 Ensembl | MGI Sequence Detail 188 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 9
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-24095
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 4
      Gene Ontology 9
      Phenotypes 12
    • Earliest
      J:23742 Stromstedt M, et al., A full-length cDNA encoding mouse adrenodoxin. Biochim Biophys Acta. 1995 Mar 14;1261(1):126-8
    • Latest
      J:348785 Zhang D, et al., Maternal Ezh1/2 deficiency impairs the function of mitochondria in mouse oocytes and early embryos. J Cell Physiol. 2024 Mar 26;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory