About   Help   FAQ
Calm2 Gene Detail
Summary
  • Symbol
    Calm2
  • Name
    calmodulin 2
  • Synonyms
    1500001E21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:103250
    NCBI Gene: 12314
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:87740840-87754363 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 57.49 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    317 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103250
 protein coding gene Chr17:87740829-87754363 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024103
 protein coding gene Chr17:90826406-90840562 (-)
A/J MGP_AJ_G0024062
 protein coding gene Chr17:87900144-87921622 (-)
AKR/J MGP_AKRJ_G0024031
 protein coding gene Chr17:89375956-89388847 (-)
BALB/cJ MGP_BALBcJ_G0024063
 protein coding gene Chr17:87751005-87764075 (-)
C3H/HeJ MGP_C3HHeJ_G0023828
 protein coding gene Chr17:90252005-90265344 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024508
 protein coding gene Chr17:93952518-93970261 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021947
 protein coding gene Chr17:83038733-83051143 (-)
CAST/EiJ MGP_CASTEiJ_G0023307
 protein coding gene Chr17:91082142-91098114 (-)
CBA/J MGP_CBAJ_G0023802
 protein coding gene Chr17:97904033-97918996 (-)
DBA/2J MGP_DBA2J_G0023930
 protein coding gene Chr17:86330113-86343835 (-)
FVB/NJ MGP_FVBNJ_G0023896
 protein coding gene Chr17:85847079-85861071 (-)
LP/J MGP_LPJ_G0024014
 protein coding gene Chr17:91618687-91631443 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023924
 protein coding gene Chr17:97772512-97793565 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024553
 protein coding gene Chr17:89894993-89910004 (-)
PWK/PhJ MGP_PWKPhJ_G0023052
 protein coding gene Chr17:85972943-85993840 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022863
 protein coding gene Chr17:86635160-86652318 (-)
WSB/EiJ MGP_WSBEiJ_G0023373
 protein coding gene Chr17:90740462-90753310 (-)



Homology
more
  • Human Ortholog
    CALM2, calmodulin 2
  • Vertebrate Orthologs
    10
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CALM2, calmodulin 2
  • Synonyms
    CALM, CALML2, caM, CAM1, CAM3, CAMC, CAMII, CAMIII, LQT15, PHKD, PHKD2
  • Links
    NCBI Gene ID: 805
    neXtProt AC: NX_P0DP23, NX_P0DP24, NX_P0DP25
    UniProt: P0DP24

  • Chr Location
    2p21; chr2:47160082-47176936 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CALM2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    141
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    863
  • Tissues
    144
  • cDNA Data
    732
  • Literature Summary
    11
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036438 Ensembl Gene Model | MGI Sequence Detail 13524 C57BL/6J ±  kb
    transcript ENSMUST00000040440 Ensembl | MGI Sequence Detail 1205 Not Applicable  
    polypeptide ENSMUSP00000048857 Ensembl | MGI Sequence Detail 149 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    Molecular
    Reagents
    less
    • All nucleic 737
      cDNA 734
      Primer pair 1
      Other 2

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-24126, MGI:1922950, MGI:2146954
    References
    more
    • Summaries
      All 57
      Developmental Gene Expression 11
      Gene Ontology 11
      Phenotypes 9
    • Earliest
      J:19936 Bender PK, et al., The abundance of calmodulin mRNAs is regulated in phosphorylase kinase-deficient skeletal muscle. J Biol Chem. 1988 Jul 15;263(20):9733-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory