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Ptprk Gene Detail
Summary
  • Symbol
    Ptprk
  • Name
    protein tyrosine phosphatase receptor type K
  • Synonyms
    PTPk, RPTPkappa
  • Feature Type
    protein coding gene
  • IDs
    MGI:103310
    NCBI Gene: 19272
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:27950816-28473393 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 15.06 cM
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    15342 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_103310
 protein coding gene Chr10:27950406-28473393 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017106
 protein coding gene Chr10:26186237-26735127 (+)
A/J MGP_AJ_G0017083
 protein coding gene Chr10:25396516-25925219 (+)
AKR/J MGP_AKRJ_G0017043
 protein coding gene Chr10:25808326-26340426 (+)
BALB/cJ MGP_BALBcJ_G0017046
 protein coding gene Chr10:25517112-26037916 (+)
C3H/HeJ MGP_C3HHeJ_G0016866
 protein coding gene Chr10:26062187-26589425 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017504
 protein coding gene Chr10:26986532-27536630 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015202
 protein coding gene Chr10:23951355-24461908 (+)
CAST/EiJ MGP_CASTEiJ_G0016445
 protein coding gene Chr10:26075309-26631506 (+)
CBA/J MGP_CBAJ_G0016840
 protein coding gene Chr10:28296143-28866395 (+)
DBA/2J MGP_DBA2J_G0016945
 protein coding gene Chr10:25107101-25633934 (+)
FVB/NJ MGP_FVBNJ_G0016940
 protein coding gene Chr10:24762559-25280886 (+)
LP/J MGP_LPJ_G0017022
 protein coding gene Chr10:26182450-26721403 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016970
 protein coding gene Chr10:28389057-28973008 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017540
 protein coding gene Chr10:25705093-26240707 (+)
PWK/PhJ MGP_PWKPhJ_G0016227
 protein coding gene Chr10:24908229-25429001 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016011
 protein coding gene Chr10:25571684-26110595 (+)
WSB/EiJ MGP_WSBEiJ_G0016508
 protein coding gene Chr10:25839876-26374165 (+)



Homology
more
  • Human Ortholog
    PTPRK, protein tyrosine phosphatase receptor type K
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PTPRK, protein tyrosine phosphatase receptor type K
  • Synonyms
    R-PTP-kappa
  • Links
    NCBI Gene ID: 5796
    neXtProt AC: NX_Q15262
    UniProt: Q15262

  • Chr Location
    6q22.33; chr6:127968785-128520616 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    965
  • Tissues
    151
  • cDNA Data
    70
  • Literature Summary
    17
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000019889 Ensembl Gene Model | MGI Sequence Detail 522578 C57BL/6J ±  kb
    transcript ENSMUST00000218276 Ensembl | MGI Sequence Detail 4754 Not Applicable  
    polypeptide ENSMUSP00000151866 Ensembl | MGI Sequence Detail 1471 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 81
      cDNA 75
      Primer pair 3
      Other 3

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGD-MRK-24194, MGI:2143696
    References
    more
    • Summaries
      All 61
      Developmental Gene Expression 17
      Gene Ontology 8
      Phenotypes 16
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:353626 Ohkawara B, et al., Transcriptome profile of subsynaptic myonuclei at the neuromuscular junction in embryogenesis. J Neurochem. 2024 Apr;168(4):342-354
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory