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Psma3 Gene Detail
Summary
  • Symbol
    Psma3
  • Name
    proteasome subunit alpha 3
  • Synonyms
    Lmpc8
  • Feature Type
    protein coding gene
  • IDs
    MGI:104883
    NCBI Gene: 19167
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:71021395-71043121 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 29.39 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    721 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104883
 protein coding gene Chr12:71016082-71043121 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019813
 protein coding gene Chr12:70755309-70775327 (+)
A/J MGP_AJ_G0019771
 protein coding gene Chr12:68109576-68135435 (+)
AKR/J MGP_AKRJ_G0019747
 protein coding gene Chr12:70149446-70171979 (+)
BALB/cJ MGP_BALBcJ_G0019751
 protein coding gene Chr12:68567325-68605291 (+)
C3H/HeJ MGP_C3HHeJ_G0019556
 protein coding gene Chr12:70628993-70650653 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020203
 protein coding gene Chr12:73005515-73028115 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017823
 protein coding gene Chr12:65619533-65639197 (+)
CAST/EiJ MGP_CASTEiJ_G0019108
 protein coding gene Chr12:65370061-65393231 (+)
CBA/J MGP_CBAJ_G0019526
 protein coding gene Chr12:75718277-75738653 (+)
DBA/2J MGP_DBA2J_G0019642
 protein coding gene Chr12:68017512-68038978 (+)
FVB/NJ MGP_FVBNJ_G0019629
 protein coding gene Chr12:66906973-66927571 (+)
LP/J MGP_LPJ_G0019714
 protein coding gene Chr12:70731890-70753875 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019668
 protein coding gene Chr12:78965910-78987426 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020238
 protein coding gene Chr12:69644870-69671710 (+)
PWK/PhJ MGP_PWKPhJ_G0018873
 protein coding gene Chr12:62294735-62318128 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018668
 protein coding gene Chr12:64007936-64029462 (+)
WSB/EiJ MGP_WSBEiJ_G0019159
 protein coding gene Chr12:70256338-70277812 (+)



Homology
more
  • Human Ortholog
    PSMA3, proteasome 20S subunit alpha 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSMA3, proteasome 20S subunit alpha 3
  • Synonyms
    HC8, PSC3
  • Links
    NCBI Gene ID: 5684
    neXtProt AC: NX_P25788
    UniProt: P25788

  • Chr Location
    14q23.1; chr14:58244843-58272012 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    992
  • Tissues
    35
  • cDNA Data
    199
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000060073 Ensembl Gene Model | MGI Sequence Detail 21727 C57BL/6J ±  kb
transcript ENSMUST00000160027 Ensembl | MGI Sequence Detail 2846 Not Applicable  
polypeptide ENSMUSP00000125548 Ensembl | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 199
    cDNA 199

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-11827, MGD-MRK-29036
References
more
  • Summaries
    All 43
    Developmental Gene Expression 3
    Gene Ontology 9
    Phenotypes 11
  • Earliest
    J:4568 Woodward EC, et al., Chromosomal mapping of the non-MHC linked proteasome genes. J Immunol. 1993;150(8):43A (Abstr.)
  • Latest
    J:256230 Shin SW, et al., Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice. Nat Commun. 2017 Nov 21;8(1):1643
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory