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Cebpg Gene Detail
Summary
  • Symbol
    Cebpg
  • Name
    CCAAT/enhancer binding protein gamma
  • Synonyms
    C/EBPgamma, GPE1-BP, Gpe1bp, Ig/EBP
  • Feature Type
    protein coding gene
  • IDs
    MGI:104982
    NCBI Gene: 12611
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:34745847-34755991 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 20.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    260 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_104982
 protein coding gene Chr7:34745847-34755998 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032081
 protein coding gene Chr7:34395202-34405356 (-)
A/J MGP_AJ_G0032061
 protein coding gene Chr7:33492529-33502679 (-)
AKR/J MGP_AKRJ_G0031994
 protein coding gene Chr7:34295134-34305281 (-)
BALB/cJ MGP_BALBcJ_G0032068
 protein coding gene Chr7:33789131-33799280 (-)
C3H/HeJ MGP_C3HHeJ_G0031785
 protein coding gene Chr7:35189710-35199859 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032545
 protein coding gene Chr7:36099247-36109397 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029578
 protein coding gene Chr7:34215860-34226030 (-)
CAST/EiJ MGP_CASTEiJ_G0031120
 protein coding gene Chr7:26326825-26336966 (-)
CBA/J MGP_CBAJ_G0031753
 protein coding gene Chr7:37234394-37244545 (-)
DBA/2J MGP_DBA2J_G0031905
 protein coding gene Chr7:33336769-33347325 (-)
FVB/NJ MGP_FVBNJ_G0031860
 protein coding gene Chr7:33267091-33277239 (-)
LP/J MGP_LPJ_G0031982
 protein coding gene Chr7:34732219-34742373 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031898
 protein coding gene Chr7:36254804-36265089 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032560
 protein coding gene Chr7:33831835-33841994 (-)
PWK/PhJ MGP_PWKPhJ_G0030842
 protein coding gene Chr7:26665743-26675909 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030677
 protein coding gene Chr7:23414441-23424626 (-)
WSB/EiJ MGP_WSBEiJ_G0031230
 protein coding gene Chr7:34386631-34396778 (-)



Homology
more
  • Human Ortholog
    CEBPG, CCAAT enhancer binding protein gamma
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEBPG, CCAAT enhancer binding protein gamma
  • Synonyms
    GPE1BP, IG/EBP-1
  • Links
    NCBI Gene ID: 1054
    neXtProt AC: NX_P53567
    UniProt: P53567

  • Chr Location
    19q13.11; chr19:33373685-33382686 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mutation of this gene results in impaired natural killer cell cytotoxic activity and IFN-gamma production.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    40
  • GO References
    17
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    764
  • Tissues
    55
  • cDNA Data
    106
  • Literature Summary
    8
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 12611 NCBI Gene Model | MGI Sequence Detail 10145 C57BL/6J ±  kb
    transcript NM_009884 RefSeq | MGI Sequence Detail 4718 C57BL/6  
    polypeptide P53568 UniProt | EBI | MGI Sequence Detail 150 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 109
      Genomic 1
      cDNA 106
      Primer pair 2

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGD-MRK-10226, MGD-MRK-31055, MGI:95796
    References
    more
    • Summaries
      All 57
      Developmental Gene Expression 8
      Gene Ontology 17
      Phenotypes 11
    • Earliest
      J:30067 Roman C, et al., Ig/EBP-1: a ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBP. Genes Dev. 1990 Aug;4(8):1404-15
    • Latest
      J:329555 Tian F, et al., Core transcription programs controlling injury-induced neurodegeneration of retinal ganglion cells. Neuron. 2022 Aug 17;110(16):2607-2624.e8
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory