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Rad23a Gene Detail
Summary
  • Symbol
    Rad23a
  • Name
    RAD23 homolog A, nucleotide excision repair protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:105126
    NCBI Gene: 19358
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:85561540-85567361 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 41.20 cM, cytoband C3
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    137 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105126
 protein coding gene Chr8:85560648-85567361 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033872
 protein coding gene Chr8:85757599-85764258 (-)
A/J MGP_AJ_G0033855
 protein coding gene Chr8:82377819-82384488 (-)
AKR/J MGP_AKRJ_G0033781
 protein coding gene Chr8:84817225-84823884 (-)
BALB/cJ MGP_BALBcJ_G0033848
 protein coding gene Chr8:82504532-82511191 (-)
C3H/HeJ MGP_C3HHeJ_G0033558
 protein coding gene Chr8:85441690-85448359 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034368
 protein coding gene Chr8:89038863-89045509 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031310
 protein coding gene Chr8:76169403-76176083 (-)
CAST/EiJ MGP_CASTEiJ_G0032888
 protein coding gene Chr8:84864448-84871102 (-)
CBA/J MGP_CBAJ_G0033534
 protein coding gene Chr8:92080862-92087531 (-)
DBA/2J MGP_DBA2J_G0033687
 protein coding gene Chr8:82017237-82024128 (-)
FVB/NJ MGP_FVBNJ_G0033635
 protein coding gene Chr8:80962623-80969292 (-)
LP/J MGP_LPJ_G0033779
 protein coding gene Chr8:85866672-85873331 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033677
 protein coding gene Chr8:94636572-94643233 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034385
 protein coding gene Chr8:84807746-84814392 (-)
PWK/PhJ MGP_PWKPhJ_G0032592
 protein coding gene Chr8:81264039-81270694 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032428
 protein coding gene Chr8:83616774-83623420 (-)
WSB/EiJ MGP_WSBEiJ_G0033001
 protein coding gene Chr8:85234452-85241111 (-)



Homology
more
  • Human Ortholog
    RAD23A, RAD23 homolog A, nucleotide excision repair protein
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAD23A, RAD23 homolog A, nucleotide excision repair protein
  • Synonyms
    HHR23A, HR23A
  • Links
    NCBI Gene ID: 5886
    neXtProt AC: NX_P54725
    UniProt: P54725

  • Chr Location
    19p13.13; chr19:12945855-12953642 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 3 alleles in 2 genetic backgrounds
    4 phenotypes from multigenic genotypes
    40 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    5
  • Radiation induced
    1
  • Targeted
    5
  • Genomic Mutations
    2 involving Rad23a
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    12 strains or lines available
Mice with a targeted disruption of this gene show no obvious phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    37
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    11
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 19358 NCBI Gene Model | MGI Sequence Detail 5822 C57BL/6J ±  kb
transcript NM_001378896 RefSeq | MGI Sequence Detail 2268 C57BL/6  
polypeptide P54726 UniProt | EBI | MGI Sequence Detail 363 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    Genomic 1
    cDNA 14
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-32167, MGI:1916893, MGI:2142661
References
more
  • Summaries
    All 72
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 40
  • Earliest
    J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
  • Latest
    J:354587 Nedomova M, et al., DDI2 protease controls embryonic development and inflammation via TCF11/NRF1. iScience. 2024 Oct 18;27(10):110893
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory