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Renbp Gene Detail
Summary
  • Symbol
    Renbp
  • Name
    renin binding protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:105940
    NCBI Gene: 19703
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:72965727-72974408 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 37.49 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    267 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_105940
 protein coding gene ChrX:72965727-72974456 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035827
 protein coding gene ChrX:69704290-69713013 (-)
A/J MGP_AJ_G0035808
 protein coding gene ChrX:69899811-69908308 (-)
AKR/J MGP_AKRJ_G0035733
 protein coding gene ChrX:71743484-71753658 (-)
BALB/cJ MGP_BALBcJ_G0035793
 protein coding gene ChrX:68926087-68934904 (-)
C3H/HeJ MGP_C3HHeJ_G0035498
 protein coding gene ChrX:70180008-70189640 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036323
 protein coding gene ChrX:71847401-71856906 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033167
 protein coding gene ChrX:68929742-68938511 (-)
CAST/EiJ MGP_CASTEiJ_G0034789
 protein coding gene ChrX:55530502-55539085 (-)
CBA/J MGP_CBAJ_G0035473
 protein coding gene ChrX:73843474-73854304 (-)
DBA/2J MGP_DBA2J_G0035630
 protein coding gene ChrX:69354772-69363500 (-)
FVB/NJ MGP_FVBNJ_G0035574
 protein coding gene ChrX:68685311-68702250 (-)
LP/J MGP_LPJ_G0035715
 protein coding gene ChrX:70485305-70495226 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035612
 protein coding gene ChrX:76395473-76405764 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036345
 protein coding gene ChrX:69526438-69535135 (-)
PWK/PhJ MGP_PWKPhJ_G0034488
 protein coding gene ChrX:53537603-53546986 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034322
 protein coding gene ChrX:56426298-56435429 (-)
WSB/EiJ MGP_WSBEiJ_G0034930
 protein coding gene ChrX:68797983-68807966 (-)



Homology
more
  • Human Ortholog
    RENBP, renin binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RENBP, renin binding protein
  • Synonyms
    RBP, RNBP
  • Links
    NCBI Gene ID: 5973
    neXtProt AC: NX_P51606
    UniProt: P51606

  • Chr Location
    Xq28; chrX:153935269-153944687 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted null mutation exhibit normal function of the renin-angiotensin system and blood pressure regulation; however, abnormalites in urine carbohydrates were noted.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    55
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 19703 NCBI Gene Model | MGI Sequence Detail 8682 C57BL/6J ±  kb
    transcript NR_189639 RefSeq | MGI Sequence Detail 1524 C57BL/6  
    polypeptide P82343 UniProt | EBI | MGI Sequence Detail 419 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 58
      Genomic 3
      cDNA 55

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-33619
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 2
      Gene Ontology 8
      Phenotypes 8
    • Earliest
      J:31839 Frattini A, et al., The chromosome localization and the HCF repeats of the human host cell factor gene (HCFC1) are conserved in the mouse homologue. Genomics. 1996 Mar 1;32(2):277-80
    • Latest
      J:287843 Tian E, et al., Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25196-25202
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory