About   Help   FAQ
Nxph2 Gene Detail
Summary
  • Symbol
    Nxph2
  • Name
    neurexophilin 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:107491
    NCBI Gene: 18232
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr2:23211258-23291985 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 15.28 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2336 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107491
 protein coding gene Chr2:23211258-23291998 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025399
 protein coding gene Chr2:21080858-21158286 (+)
A/J MGP_AJ_G0025377
 protein coding gene Chr2:20249766-20338952 (+)
AKR/J MGP_AKRJ_G0025346
 protein coding gene Chr2:20936376-21022730 (+)
BALB/cJ MGP_BALBcJ_G0025372
 protein coding gene Chr2:20340678-20427255 (+)
C3H/HeJ MGP_C3HHeJ_G0025133
 protein coding gene Chr2:20871709-20959362 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025816
 protein coding gene Chr2:21680005-21780049 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023228
 protein coding gene Chr2:19322335-19402148 (+)
CAST/EiJ MGP_CASTEiJ_G0024596
 protein coding gene Chr2:20778407-20860956 (+)
CBA/J MGP_CBAJ_G0025111
 protein coding gene Chr2:22544787-22638550 (+)
DBA/2J MGP_DBA2J_G0025244
 protein coding gene Chr2:20114180-20200971 (+)
FVB/NJ MGP_FVBNJ_G0025206
 protein coding gene Chr2:19888551-19971990 (+)
LP/J MGP_LPJ_G0025330
 protein coding gene Chr2:21025511-21111038 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025237
 protein coding gene Chr2:22601715-22720166 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025875
 protein coding gene Chr2:20857347-20960644 (+)
PWK/PhJ MGP_PWKPhJ_G0024345
 protein coding gene Chr2:19943421-20022539 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024145
 protein coding gene Chr2:20941111-21046397 (+)
WSB/EiJ MGP_WSBEiJ_G0024666
 protein coding gene Chr2:20986191-21071776 (+)



Homology
more
  • Human Ortholog
    NXPH2, neurexophilin 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NXPH2, neurexophilin 2
  • Synonyms
    NPH2
  • Links
    NCBI Gene ID: 11249
    neXtProt AC: NX_O95156
    UniProt: O95156

  • Chr Location
    2q22.1; chr2:138669157-138780390 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000069132 Ensembl Gene Model | MGI Sequence Detail 80728 C57BL/6J ±  kb
transcript ENSMUST00000102945 Ensembl | MGI Sequence Detail 2579 Not Applicable  
polypeptide ENSMUSP00000100009 Ensembl | MGI Sequence Detail 261 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 5
    Genomic 1
    cDNA 4

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-36059
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:34033 Petrenko AG, et al., Structure and evolution of neurexophilin. J Neurosci. 1996 Jul 15;16(14):4360-9
  • Latest
    J:305858 Morarach K, et al., Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing. Nat Neurosci. 2021 Jan;24(1):34-46
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory