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Larp7 Gene Detail
Summary
  • Symbol
    Larp7
  • Name
    La ribonucleoprotein 7, transcriptional regulator
  • Synonyms
    C330027G06Rik, D3Wsu161e
  • Feature Type
    protein coding gene
  • IDs
    MGI:107634
    NCBI Gene: 28036
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:127330363-127346998 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 56.54 cM, cytoband H1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    466 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107634
 protein coding gene Chr3:127330363-127346998 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027860
 protein coding gene Chr3:130026081-130045898 (-)
A/J MGP_AJ_G0027819
 protein coding gene Chr3:125578346-125595659 (-)
AKR/J MGP_AKRJ_G0027784
 protein coding gene Chr3:128825229-128842476 (-)
BALB/cJ MGP_BALBcJ_G0027831
 protein coding gene Chr3:125439087-125457471 (-)
C3H/HeJ MGP_C3HHeJ_G0027561
 protein coding gene Chr3:129205030-129221233 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028276
 protein coding gene Chr3:134719060-134743561 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025613
 protein coding gene Chr3:120831482-120847223 (-)
CAST/EiJ MGP_CASTEiJ_G0027017
 protein coding gene Chr3:128749788-128770107 (-)
CBA/J MGP_CBAJ_G0027536
 protein coding gene Chr3:139276267-139297690 (-)
DBA/2J MGP_DBA2J_G0027677
 protein coding gene Chr3:124799167-124816437 (-)
FVB/NJ MGP_FVBNJ_G0027645
 protein coding gene Chr3:122363891-122380826 (-)
LP/J MGP_LPJ_G0027787
 protein coding gene Chr3:131577291-131595434 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027675
 protein coding gene Chr3:147198061-147216617 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028332
 protein coding gene Chr3:128460865-128478578 (-)
PWK/PhJ MGP_PWKPhJ_G0026742
 protein coding gene Chr3:124518610-124537284 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026566
 protein coding gene Chr3:126544311-126563694 (-)
WSB/EiJ MGP_WSBEiJ_G0027096
 protein coding gene Chr3:129178629-129198002 (-)



Homology
more
  • Human Ortholog
    LARP7, La ribonucleoprotein 7, transcriptional regulator
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LARP7, La ribonucleoprotein 7, transcriptional regulator
  • Synonyms
    ALAZS, HDCMA18P, hLARP7, PIP7S
  • Links
    NCBI Gene ID: 51574
    neXtProt AC: NX_Q4G0J3
    UniProt: Q4G0J3

  • Chr Location
    4q25; chr4:112637077-112657696 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display complete perinatal lethality and a decrease in primordial germ cell number and proliferation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    33
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    773
  • Tissues
    40
  • cDNA Data
    22
  • Literature Summary
    14
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 28036 NCBI Gene Model | MGI Sequence Detail 16636 C57BL/6J ±  kb
transcript NM_138593 RefSeq | MGI Sequence Detail 2135 ZRU/MplStud  
polypeptide Q05CL8 UniProt | EBI | MGI Sequence Detail 570 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 22
    Primer pair 4
    Other 1

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-36208, MGI:1915530
References
more
  • Summaries
    All 58
    Developmental Gene Expression 14
    Diseases 1
    Gene Ontology 7
    Phenotypes 20
  • Earliest
    J:34518 Kerr SM, et al., Ott, a mouse X-linked multigene family expressed specifically during meiosis. Hum Mol Genet. 1996 Aug;5(8):1139-48
  • Latest
    J:359127 Wang M, et al., Extra-cerebral recombination activity of Emx1-Cre and nestin-Cre in the kidney. Front Cell Dev Biol. 2024;12:1480217
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory