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Uqcrq Gene Detail
Summary
  • Symbol
    Uqcrq
  • Name
    ubiquinol-cytochrome c reductase, complex III subunit VII
  • Synonyms
    1100001F06Rik, 1500040F11Rik, 5830407L17Rik, c1502, Qpc, QP-C
  • Feature Type
    protein coding gene
  • IDs
    MGI:107807
    NCBI Gene: 22272
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:53318749-53321658 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 31.94 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    192 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107807
 protein coding gene Chr11:53318749-53321658 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018291
 protein coding gene Chr11:52809318-52812227 (-)
A/J MGP_AJ_G0018260
 protein coding gene Chr11:50829152-50832061 (-)
AKR/J MGP_AKRJ_G0018230
 protein coding gene Chr11:52484138-52487047 (-)
BALB/cJ MGP_BALBcJ_G0018231
 protein coding gene Chr11:51186581-51189490 (-)
C3H/HeJ MGP_C3HHeJ_G0018042
 protein coding gene Chr11:52456420-52459329 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018683
 protein coding gene Chr11:54403840-54406749 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016333
 protein coding gene Chr11:48368277-48371179 (-)
CAST/EiJ MGP_CASTEiJ_G0017607
 protein coding gene Chr11:52501790-52504691 (-)
CBA/J MGP_CBAJ_G0018017
 protein coding gene Chr11:56974177-56977086 (-)
DBA/2J MGP_DBA2J_G0018127
 protein coding gene Chr11:50577559-50580461 (-)
FVB/NJ MGP_FVBNJ_G0018119
 protein coding gene Chr11:50215884-50218793 (-)
LP/J MGP_LPJ_G0018201
 protein coding gene Chr11:53262919-53265828 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018143
 protein coding gene Chr11:58302563-58305444 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018725
 protein coding gene Chr11:52514298-52517206 (-)
PWK/PhJ MGP_PWKPhJ_G0017382
 protein coding gene Chr11:51091261-51094158 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017177
 protein coding gene Chr11:52336788-52339699 (-)
WSB/EiJ MGP_WSBEiJ_G0017654
 protein coding gene Chr11:52155772-52158653 (-)



Homology
more
  • Human Ortholog
    UQCRQ, ubiquinol-cytochrome c reductase complex III subunit VII
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UQCRQ, ubiquinol-cytochrome c reductase complex III subunit VII
  • Synonyms
    MC3DN4, QCR8, QP-C, QPC, UQCR7
  • Links
    NCBI Gene ID: 27089
    neXtProt AC: NX_O14949
    UniProt: O14949

  • Chr Location
    5q31.1; chr5:132866630-132868847 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human UQCRQ associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    879
  • Tissues
    134
  • cDNA Data
    264
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22272 NCBI Gene Model | MGI Sequence Detail 2910 C57BL/6J ±  kb
transcript NM_025352 RefSeq | MGI Sequence Detail 1525 Not Specified  
polypeptide Q9CQ69 UniProt | EBI | MGI Sequence Detail 82 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 271
    cDNA 266
    Primer pair 3
    Other 2

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-36384, MGI:1913349, MGI:1915190, MGI:1923247, MGI:2138135
References
more
  • Summaries
    All 63
    Developmental Gene Expression 8
    Gene Ontology 12
    Phenotypes 21
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:355679 Vercellino I, et al., SCAF1 drives the compositional diversity of mammalian respirasomes. Nat Struct Mol Biol. 2024 Jul;31(7):1061-1071
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory