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Lad1 Gene Detail
Summary
  • Symbol
    Lad1
  • Name
    ladinin
  • Feature Type
    protein coding gene
  • IDs
    MGI:109343
    NCBI Gene: 16763
  • Alliance
    gene page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:135746336-135761079 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 59.30 cM, cytoband E4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    470 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109343
 protein coding gene Chr1:135746336-135761080 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016529
 protein coding gene Chr1:139604435-139620992 (+)
A/J MGP_AJ_G0016512
 protein coding gene Chr1:134323009-134337444 (+)
AKR/J MGP_AKRJ_G0016477
 protein coding gene Chr1:138317988-138334903 (+)
BALB/cJ MGP_BALBcJ_G0016472
 protein coding gene Chr1:134642795-134657883 (+)
C3H/HeJ MGP_C3HHeJ_G0016298
 protein coding gene Chr1:138418067-138432558 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016933
 protein coding gene Chr1:144632669-144647217 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014644
 protein coding gene Chr1:127427674-127442437 (+)
CAST/EiJ MGP_CASTEiJ_G0015878
 protein coding gene Chr1:137500191-137514748 (+)
CBA/J MGP_CBAJ_G0016271
 protein coding gene Chr1:149634584-149649106 (+)
DBA/2J MGP_DBA2J_G0016377
 protein coding gene Chr1:133317222-133332304 (+)
FVB/NJ MGP_FVBNJ_G0016376
 protein coding gene Chr1:131963539-131978655 (+)
LP/J MGP_LPJ_G0016448
 protein coding gene Chr1:140837840-140852392 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016401
 protein coding gene Chr1:155294969-155309480 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016969
 protein coding gene Chr1:138087794-138102331 (+)
PWK/PhJ MGP_PWKPhJ_G0015664
 protein coding gene Chr1:132355897-132370984 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015451
 protein coding gene Chr1:137067458-137082089 (+)
WSB/EiJ MGP_WSBEiJ_G0015941
 protein coding gene Chr1:138122486-138138480 (+)



Homology
more
  • Human Ortholog
    LAD1, ladinin 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LAD1, ladinin 1
  • Synonyms
    LadA
  • Links
    NCBI Gene ID: 3898
    neXtProt AC: NX_O00515
    UniProt: O00515

  • Chr Location
    1q32.1; chr1:201380833-201399915 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    4
  • Radiation induced
    1
  • Genomic Mutations
    3 involving Lad1
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    31 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    807
  • Tissues
    16
  • cDNA Data
    74
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 16763 NCBI Gene Model | MGI Sequence Detail 14744 C57BL/6J ±  kb
transcript NM_133664 RefSeq | MGI Sequence Detail 2992 C57BL/6  
polypeptide P57016 UniProt | EBI | MGI Sequence Detail 528 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 76
    Genomic 2
    cDNA 74

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-38388
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:220468 Walentin K, et al., A Grhl2-dependent gene network controls trophoblast branching morphogenesis. Development. 2015 Mar 15;142(6):1125-36
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory