About   Help   FAQ
Gimap1 Gene Detail
Summary
  • Symbol
    Gimap1
  • Name
    GTPase, IMAP family member 1
  • Synonyms
    38kDa, IAP38, imap, Imap38
  • Feature Type
    protein coding gene
  • IDs
    MGI:109368
    NCBI Gene: 16205
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:48715988-48720729 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 23.69 cM, cytoband B
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    319 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_109368
 protein coding gene Chr6:48715981-48720729 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030710
 protein coding gene Chr6:47696451-47701189 (+)
A/J MGP_AJ_G0030681
 protein coding gene Chr6:45530512-45536152 (+)
AKR/J MGP_AKRJ_G0030606
 protein coding gene Chr6:47129348-47134080 (+)
BALB/cJ MGP_BALBcJ_G0030691
 protein coding gene Chr6:45862581-45867460 (+)
C3H/HeJ MGP_C3HHeJ_G0030404
 protein coding gene Chr6:47138707-47143365 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031146
 protein coding gene Chr6:48817744-48822440 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028353
 protein coding gene Chr6:43159056-43162594 (+)
CAST/EiJ MGP_CASTEiJ_G0029808
 protein coding gene Chr6:46860961-46865764 (+)
CBA/J MGP_CBAJ_G0030379
 protein coding gene Chr6:50839042-50844510 (+)
DBA/2J MGP_DBA2J_G0030528
 protein coding gene Chr6:45447199-45451902 (+)
FVB/NJ MGP_FVBNJ_G0030480
 protein coding gene Chr6:45080724-45085458 (+)
LP/J MGP_LPJ_G0030613
 protein coding gene Chr6:47675772-47681783 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030514
 protein coding gene Chr6:53652147-53658062 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031175
 protein coding gene Chr6:46997016-47002759 (+)
PWK/PhJ MGP_PWKPhJ_G0029520
 protein coding gene Chr6:44978946-44984131 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029356
 protein coding gene Chr6:46343191-46347907 (+)
WSB/EiJ MGP_WSBEiJ_G0029885
 protein coding gene Chr6:46998253-47002990 (+)



Homology
more
  • Human Ortholog
    GIMAP1, GTPase, IMAP family member 1
  • Vertebrate Orthologs
    9
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GIMAP1, GTPase, IMAP family member 1
  • Synonyms
    HIMAP1, IAN2, IMAP1, IMAP38
  • Links
    NCBI Gene ID: 170575
    neXtProt AC: NX_Q8WWP7
    UniProt: Q8WWP7

  • Chr Location
    7q36.1; chr7:150716606-150724284 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 2 alleles in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele have defects in the development of mature B and T lymphocytes.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    16
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000090019 Ensembl Gene Model | MGI Sequence Detail 4742 C57BL/6J ±  kb
    transcript ENSMUST00000054368 Ensembl | MGI Sequence Detail 1493 Not Applicable  
    polypeptide ENSMUSP00000062108 Ensembl | MGI Sequence Detail 300 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      Genomic 1
      cDNA 16

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-38413
    References
    more
    • Summaries
      All 30
      Gene Ontology 5
      Phenotypes 6
    • Earliest
      J:38420 Krucken J, et al., Novel gene expressed in spleen cells mediating acquired testosterone-resistant immunity to Plasmodium chabaudi malaria. Biochem Biophys Res Commun. 1997 Jan 3;230(1):167-70
    • Latest
      J:247251 Datta P, et al., Survival of mature T cells in the periphery is intrinsically dependent on GIMAP1 in mice. Eur J Immunol. 2017 Jan;47(1):84-93
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory