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Kif16b Gene Detail
Summary
  • Symbol
    Kif16b
  • Name
    kinesin family member 16B
  • Synonyms
    8430434E15Rik, mKIAA1590, N-3 kinesin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1098240
    NCBI Gene: 16558
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:142459394-142743451 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 70.67 cM, cytoband G3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6941 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1098240
 protein coding gene Chr2:142459394-142743535 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026573
 protein coding gene Chr2:146613379-146906608 (-)
A/J MGP_AJ_G0026537
 protein coding gene Chr2:140662956-140947948 (-)
AKR/J MGP_AKRJ_G0026511
 protein coding gene Chr2:144732616-145024083 (-)
BALB/cJ MGP_BALBcJ_G0026549
 protein coding gene Chr2:141134018-141416383 (-)
C3H/HeJ MGP_C3HHeJ_G0026292
 protein coding gene Chr2:145274947-145566239 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026994
 protein coding gene Chr2:151020261-151328883 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024371
 protein coding gene Chr2:134955870-135229533 (-)
CAST/EiJ MGP_CASTEiJ_G0025753
 protein coding gene Chr2:145617380-145907633 (-)
CBA/J MGP_CBAJ_G0026272
 protein coding gene Chr2:156561364-156867980 (-)
DBA/2J MGP_DBA2J_G0026406
 protein coding gene Chr2:140018368-140292920 (-)
FVB/NJ MGP_FVBNJ_G0026370
 protein coding gene Chr2:138573903-138852953 (-)
LP/J MGP_LPJ_G0026510
 protein coding gene Chr2:146792289-147089751 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026390
 protein coding gene Chr2:160775094-161077407 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027049
 protein coding gene Chr2:144745753-145031718 (-)
PWK/PhJ MGP_PWKPhJ_G0025489
 protein coding gene Chr2:139653093-139935118 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025290
 protein coding gene Chr2:143785245-144092459 (-)
WSB/EiJ MGP_WSBEiJ_G0025826
 protein coding gene Chr2:145730292-146022259 (-)



Homology
more
  • Human Ortholog
    KIF16B, kinesin family member 16B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KIF16B, kinesin family member 16B
  • Synonyms
    C20orf23, KISC20ORF, SNX23
  • Links
    NCBI Gene ID: 55614
    neXtProt AC: NX_Q96L93
    UniProt: Q96L93

  • Chr Location
    20p12.1; chr20:16272104-16573448 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Chimera embryos containing a knock-out allele and derived from tetraploid rescue exhibit lethal growth arrest at the blastocyst stage with abnormal development of the primitive endoderm, epiblast epithelium, and basement membrane.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    45
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    15
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038844 Ensembl Gene Model | MGI Sequence Detail 284058 C57BL/6J ±  kb
    transcript ENSMUST00000211861 Ensembl | MGI Sequence Detail 4523 Not Applicable  
    polypeptide ENSMUSP00000148731 Ensembl | MGI Sequence Detail 1386 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 15

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1918790, MGI:2139053, MGI:2139499, MGI:2139511, MGI:3034217
    References
    more
    • Summaries
      All 48
      Gene Ontology 9
      Phenotypes 13
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory