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Rhox6 Gene Detail
Summary
  • Symbol
    Rhox6
  • Name
    reproductive homeobox 6
  • Synonyms
    Psx1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1202888
    NCBI Gene: 19202
  • Member of
    Rhox cluster
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:36915932-36918734 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 22.08 cM, cytoband A2-A4
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    17 from dbSNP Build 142
  • Strain Annotations
    13
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1202888
 protein coding gene ChrX:36915787-36918734 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035654
 protein coding gene ChrX:32831969-32834994 (-)
A/J MGP_AJ_G0035640
 protein coding gene ChrX:32908761-32911841 (-)
AKR/J MGP_AKRJ_G0035556
 protein coding gene ChrX:33557094-33560436 (+)
BALB/cJ MGP_BALBcJ_G0035623
 protein coding gene ChrX:32589024-32597900 (-)
C3H/HeJ MGP_C3HHeJ_G0035328
 protein coding gene ChrX:33162606-33165315 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036153
 protein coding gene ChrX:33539948-33541793 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033005
 protein coding gene ChrX:31202727-31205670 (+)
CAST/EiJ MGP_CASTEiJ_G0034618
 protein coding gene ChrX:21188507-21191459 (-)
CBA/J no annotation
DBA/2J MGP_DBA2J_G0035454
 protein coding gene ChrX:32652815-32662113 (+)
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ MGP_NODShiLtJ_G0035443
 protein coding gene ChrX:34753649-34756922 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036171
 protein coding gene ChrX:32765408-32771674 (+)
PWK/PhJ MGP_PWKPhJ_G0034320
 protein coding gene ChrX:20690918-20712570 (+)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    RHOXF2, Rhox homeobox family member 2
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RHOXF2, Rhox homeobox family member 2
  • Synonyms
    CT107, PEPP-2, PEPP2, THG1
  • Links
    NCBI Gene ID: 84528
    neXtProt AC: NX_Q9BQY4
    UniProt: Q9BQY4

  • Chr Location
    Xq24; chrX:120158613-120165630 (+)  GRCh38
  • Human Ortholog
    RHOXF2B, Rhox homeobox family member 2B
  • Links
    NCBI Gene ID: 727940
    neXtProt AC: NX_P0C7M4
    UniProt: P0C7M4

  • Chr Location
    Xq24; chrX:120072264-120077690 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1038
  • Tissues
    230
  • cDNA Data
    22
  • Literature Summary
    18
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 19202 NCBI Gene Model | MGI Sequence Detail 2803 C57BL/6J ±  kb
transcript NM_008955 RefSeq | MGI Sequence Detail 882 Not Specified  
polypeptide NP_032981 RefSeq | MGI Sequence Detail 227 Not Specified  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001356 Homeobox domain
    IPR009057 Homeobox-like domain superfamily
Molecular
Reagents
less
  • All nucleic 30
    Genomic 1
    cDNA 22
    Primer pair 6
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147982, MGI:2148022
References
more
  • Summaries
    All 44
    Developmental Gene Expression 18
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:46103 Han YJ, et al., Psx, a novel murine homeobox gene expressed in placenta. Gene. 1998 Jan 30;207(2):159-66
  • Latest
    J:306454 Tan K, et al., The Rhox gene cluster suppresses germline LINE1 transposition. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024785118
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory