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Ccnk Gene Detail
Summary
  • Symbol
    Ccnk
  • Name
    cyclin K
  • Synonyms
    CPR4, CycK
  • Feature Type
    protein coding gene
  • IDs
    MGI:1276106
    NCBI Gene: 12454
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:108145838-108169618 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 59.23 cM, cytoband F1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    636 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1276106
 protein coding gene Chr12:108145543-108170252 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020101
 protein coding gene Chr12:110261613-110287734 (+)
A/J MGP_AJ_G0020055
 protein coding gene Chr12:106109373-106132970 (+)
AKR/J MGP_AKRJ_G0020031
 protein coding gene Chr12:109176837-109199878 (+)
BALB/cJ MGP_BALBcJ_G0020041
 protein coding gene Chr12:106512293-106536310 (+)
C3H/HeJ MGP_C3HHeJ_G0019843
 protein coding gene Chr12:109618026-109640987 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020486
 protein coding gene Chr12:113650765-113676172 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018098
 protein coding gene Chr12:102642942-102666874 (+)
CAST/EiJ MGP_CASTEiJ_G0019385
 protein coding gene Chr12:104538982-104567137 (+)
CBA/J MGP_CBAJ_G0019810
 protein coding gene Chr12:118159853-118193897 (+)
DBA/2J MGP_DBA2J_G0019927
 protein coding gene Chr12:105631943-105655456 (+)
FVB/NJ MGP_FVBNJ_G0019912
 protein coding gene Chr12:104410280-104435116 (+)
LP/J MGP_LPJ_G0020002
 protein coding gene Chr12:110140440-110163660 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019950
 protein coding gene Chr12:121389076-121416599 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020515
 protein coding gene Chr12:108632693-108656792 (+)
PWK/PhJ MGP_PWKPhJ_G0019144
 protein coding gene Chr12:100242071-100266759 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018948
 protein coding gene Chr12:102846979-102874985 (+)
WSB/EiJ MGP_WSBEiJ_G0019442
 protein coding gene Chr12:109576552-109603296 (+)



Homology
more
  • Human Ortholog
    CCNK, cyclin K
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCNK, cyclin K
  • Synonyms
    CPR4, IDDHDF
  • Links
    NCBI Gene ID: 8812
    neXtProt AC: NX_O75909
    UniProt: O75909

  • Chr Location
    14q32.2; chr14:99481169-99535044 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap allele display complete embryonic lethality before implantation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    25
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    730
  • Tissues
    17
  • cDNA Data
    45
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021258 Ensembl Gene Model | MGI Sequence Detail 23781 C57BL/6J ±  kb
transcript ENSMUST00000221167 Ensembl | MGI Sequence Detail 2789 Not Applicable  
polypeptide ENSMUSP00000152784 Ensembl | MGI Sequence Detail 582 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 48
    cDNA 47
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145008, MGI:2145025
References
more
  • Summaries
    All 47
    Developmental Gene Expression 5
    Gene Ontology 11
    Phenotypes 10
  • Earliest
    J:48311 Edwards MC, et al., Human cyclin K, a novel RNA polymerase II-associated cyclin possessing both carboxy-terminal domain kinase and Cdk-activating kinase activity. Mol Cell Biol. 1998 Jul;18(7):4291-300
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory