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Cpsf4l Gene Detail
Summary
  • Symbol
    Cpsf4l
  • Name
    cleavage and polyadenylation specific factor 4-like
  • Synonyms
    0610010C04Rik, 1500000C01Rik, D11Ertd636e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277182
    NCBI Gene: 52670
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:113588998-113600843 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 79.17 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    565 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1277182
 protein coding gene Chr11:113588997-113601125 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019353
 protein coding gene Chr11:117528615-117540645 (-)
A/J MGP_AJ_G0019322
 protein coding gene Chr11:112466222-112478804 (-)
AKR/J MGP_AKRJ_G0019290
 protein coding gene Chr11:115776166-115788381 (-)
BALB/cJ MGP_BALBcJ_G0019295
 protein coding gene Chr11:112874841-112887948 (-)
C3H/HeJ MGP_C3HHeJ_G0019104
 protein coding gene Chr11:116130194-116143609 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019746
 protein coding gene Chr11:121053271-121066331 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017369
 protein coding gene Chr11:109542640-109555038 (-)
CAST/EiJ MGP_CASTEiJ_G0018658
 protein coding gene Chr11:117400536-117416054 (-)
CBA/J MGP_CBAJ_G0019074
 protein coding gene Chr11:125985497-125999311 (-)
DBA/2J MGP_DBA2J_G0019186
 protein coding gene Chr11:111902479-111914917 (-)
FVB/NJ MGP_FVBNJ_G0019177
 protein coding gene Chr11:111380900-111392692 (-)
LP/J MGP_LPJ_G0019256
 protein coding gene Chr11:117969069-117981624 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019208
 protein coding gene Chr11:125136547-125153359 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019783
 protein coding gene Chr11:116428402-116444485 (-)
PWK/PhJ MGP_PWKPhJ_G0018423
 protein coding gene Chr11:113114623-113127336 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018215
 protein coding gene Chr11:116237132-116250611 (-)
WSB/EiJ MGP_WSBEiJ_G0018710
 protein coding gene Chr11:116388524-116401350 (-)



Homology
more
  • Human Ortholog
    CPSF4L, cleavage and polyadenylation specific factor 4 like
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CPSF4L, cleavage and polyadenylation specific factor 4 like
  • Links
    NCBI Gene ID: 642843
    neXtProt AC: NX_A6NMK7
    UniProt: A6NMK7

  • Chr Location
    17q25.1; chr17:73242101-73263778 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    29
  • cDNA Data
    25
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000018727 Ensembl Gene Model | MGI Sequence Detail 11846 C57BL/6J ±  kb
    transcript ENSMUST00000100248 Ensembl | MGI Sequence Detail 1375 Not Applicable  
    polypeptide ENSMUSP00000097819 Ensembl | MGI Sequence Detail 280 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      8 Sequences
    • InterPro Domains
      IPR045348 CPSF complex subunit CPSF4-like
      IPR000571 Zinc finger, CCCH-type
      IPR036855 Zinc finger, CCCH-type superfamily
    Molecular
    Reagents
    less
    • All nucleic 26
      cDNA 25
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1915590, MGI:1924153
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 9
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory