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Thumpd3 Gene Detail
Summary
  • Symbol
    Thumpd3
  • Name
    THUMP domain containing 3
  • Synonyms
    Gtrosa26as
  • Feature Type
    protein coding gene
  • IDs
    MGI:1277973
    NCBI Gene: 14911
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:113023292-113045239 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 52.73 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    455 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1277973
 protein coding gene Chr6:113023186-113045239 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031111
 protein coding gene Chr6:115525229-115549548 (+)
A/J MGP_AJ_G0031080
 protein coding gene Chr6:111116282-111140244 (+)
AKR/J MGP_AKRJ_G0031011
 protein coding gene Chr6:114106200-114129459 (+)
BALB/cJ MGP_BALBcJ_G0031091
 protein coding gene Chr6:111064751-111087376 (+)
C3H/HeJ MGP_C3HHeJ_G0030617
 protein coding gene Chr6:70171470-70194777 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031550
 protein coding gene Chr6:118532015-118560639 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028714
 protein coding gene Chr6:108125047-108147983 (+)
CAST/EiJ MGP_CASTEiJ_G0030198
 protein coding gene Chr6:114528373-114551099 (+)
CBA/J MGP_CBAJ_G0030777
 protein coding gene Chr6:123214883-123241426 (+)
DBA/2J MGP_DBA2J_G0030930
 protein coding gene Chr6:110204031-110226065 (+)
FVB/NJ MGP_FVBNJ_G0030884
 protein coding gene Chr6:109194738-109217191 (+)
LP/J MGP_LPJ_G0031010
 protein coding gene Chr6:115582131-115606742 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030918
 protein coding gene Chr6:127501119-127523873 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031577
 protein coding gene Chr6:114118850-114142844 (+)
PWK/PhJ MGP_PWKPhJ_G0029914
 protein coding gene Chr6:109146984-109169892 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029742
 protein coding gene Chr6:112937998-112960444 (+)
WSB/EiJ MGP_WSBEiJ_G0030282
 protein coding gene Chr6:114487658-114510366 (+)



Homology
more
  • Human Ortholog
    THUMPD3, THUMP domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    THUMPD3, THUMP domain containing 3
  • Links
    NCBI Gene ID: 25917
    neXtProt AC: NX_Q9BV44
    UniProt: Q9BV44

  • Chr Location
    3p25.3; chr3:9362971-9386791 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    750
  • Tissues
    28
  • cDNA Data
    91
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 14911 NCBI Gene Model | MGI Sequence Detail 21948 C57BL/6J ±  kb
transcript NM_001409955 RefSeq | MGI Sequence Detail 2706 ZRU/MplStud  
polypeptide P97770 UniProt | EBI | MGI Sequence Detail 505 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000032109 tRNA (guanine(6)-N2)-methyltransferase THUMP3
    (term hierarchy)
  • EC
    2.1.1.256
  • InterPro Domains
    IPR000241 Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
    IPR004114 THUMP domain
Molecular
Reagents
less
  • All nucleic 94
    Genomic 1
    cDNA 92
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2141705
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:79478 Friedrich G, et al., Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev. 1991 Sep;5(9):1513-23
  • Latest
    J:330636 Iwata S, et al., An efficient i-GONAD method for creating and maintaining lethal mutant mice using an inversion balancer identified from the C3H/HeJJcl strain. G3 (Bethesda). 2021;11(8)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory