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Ppp1r10 Gene Detail
Summary
  • Symbol
    Ppp1r10
  • Name
    protein phosphatase 1, regulatory subunit 10
  • Synonyms
    2610025H06Rik, D17Ertd808e, PNUTS
  • Feature Type
    protein coding gene
  • IDs
    MGI:1289273
    NCBI Gene: 52040
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:36227404-36243175 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 18.77 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1289273
 protein coding gene Chr17:36227326-36243175 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023662
 protein coding gene Chr17:36124014-36138988 (+)
A/J MGP_AJ_G0023617
 protein coding gene Chr17:34999802-35043400 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0023622
 protein coding gene Chr17:35147348-35180617 (+)
C3H/HeJ MGP_C3HHeJ_G0023388
 protein coding gene Chr17:35895169-35910878 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024064
 protein coding gene Chr17:37595158-37623763 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021542
 protein coding gene Chr17:32692425-32708272 (+)
CAST/EiJ MGP_CASTEiJ_G0022879
 protein coding gene Chr17:36009462-36024131 (+)
CBA/J MGP_CBAJ_G0023366
 protein coding gene Chr17:39176134-39194654 (+)
DBA/2J MGP_DBA2J_G0023490
 protein coding gene Chr17:34304264-34323223 (+)
FVB/NJ MGP_FVBNJ_G0023461
 protein coding gene Chr17:34100711-34119074 (+)
LP/J MGP_LPJ_G0023570
 protein coding gene Chr17:36507712-36524648 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023482
 protein coding gene Chr17:37949325-37991176 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024107
 protein coding gene Chr17:35743822-35759158 (+)
PWK/PhJ MGP_PWKPhJ_G0022630
 protein coding gene Chr17:33164087-33180308 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022449
 protein coding gene Chr17:33795438-33810150 (+)
WSB/EiJ MGP_WSBEiJ_G0022945
 protein coding gene Chr17:35898261-35914000 (+)



Homology
more
  • Human Ortholog
    PPP1R10, protein phosphatase 1 regulatory subunit 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP1R10, protein phosphatase 1 regulatory subunit 10
  • Synonyms
    CAT53, FB19, p99, PNUTS, PP1R10, R111
  • Links
    NCBI Gene ID: 5514
    neXtProt AC: NX_Q96QC0
    UniProt: Q96QC0

  • Chr Location
    6p21.33; chr6:30600413-30618612 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E7.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    727
  • Tissues
    16
  • cDNA Data
    16
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 52040 NCBI Gene Model | MGI Sequence Detail 15772 C57BL/6J ±  kb
transcript NM_001403564 RefSeq | MGI Sequence Detail 4242 ZRU/MplStud  
polypeptide Q80W00 UniProt | EBI | MGI Sequence Detail 888 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000013105 serine/threonine-protein phosphatase 1 regulatory subunit 10
    (term hierarchy)
  • InterPro Domains
    IPR042805 Proline-rich protein 3
    IPR035441 TFIIS/LEDGF domain superfamily
    IPR003617 Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type
    IPR017923 Transcription factor IIS, N-terminal
    IPR000571 Zinc finger, CCCH-type
    IPR036855 Zinc finger, CCCH-type superfamily
  • GlyGen
    Q80W00 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 19
    cDNA 17
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1913700
References
more
  • Summaries
    All 42
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:190754 Ermakova O, et al., Construction and phenotypic analysis of mice carrying a duplication of the major histocompatibility class I (MHC-I) locus. Mamm Genome. 2012 Aug;23(7-8):443-53
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory