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Dop1a Gene Detail
Summary
  • Symbol
    Dop1a
  • Name
    DOP1 leucine zipper like protein A
  • Synonyms
    B130005I07Rik, D9Ertd809e, Dopey1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1289294
    NCBI Gene: 320615
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:86349194-86436683 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 46.58 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2277 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1289294
 protein coding gene Chr9:86349194-86437976 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035095
 protein coding gene Chr9:87289103-87385683 (+)
A/J MGP_AJ_G0035076
 protein coding gene Chr9:84239228-84340805 (+)
AKR/J MGP_AKRJ_G0035004
 protein coding gene Chr9:86242187-86331753 (+)
BALB/cJ MGP_BALBcJ_G0035064
 protein coding gene Chr9:83879957-83976919 (+)
C3H/HeJ MGP_C3HHeJ_G0034776
 protein coding gene Chr9:86701871-86794033 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035588
 protein coding gene Chr9:89636547-89739757 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032495
 protein coding gene Chr9:83026122-83100880 (+)
CAST/EiJ MGP_CASTEiJ_G0034094
 protein coding gene Chr9:87179432-87270513 (+)
CBA/J MGP_CBAJ_G0034749
 protein coding gene Chr9:92845245-92931275 (+)
DBA/2J MGP_DBA2J_G0034907
 protein coding gene Chr9:83787231-83881534 (+)
FVB/NJ MGP_FVBNJ_G0034850
 protein coding gene Chr9:82901807-82988602 (+)
LP/J MGP_LPJ_G0034988
 protein coding gene Chr9:87506509-87598007 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034892
 protein coding gene Chr9:94423460-94518678 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035608
 protein coding gene Chr9:86354348-86442591 (+)
PWK/PhJ MGP_PWKPhJ_G0033798
 protein coding gene Chr9:83977228-84065411 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033634
 protein coding gene Chr9:86558527-86654225 (+)
WSB/EiJ MGP_WSBEiJ_G0034211
 protein coding gene Chr9:86384811-86477726 (+)



Homology
more
  • Human Ortholog
    DOP1A, DOP1 leucine zipper like protein A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DOP1A, DOP1 leucine zipper like protein A
  • Synonyms
    dJ202D23.2, DOP1, DOPEY1, KIAA1117
  • Links
    NCBI Gene ID: 23033
    neXtProt AC: NX_Q5JWR5
    UniProt: Q5JWR5

  • Chr Location
    6q14.1; chr6:83067666-83171350 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    6
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    4
  • cDNA Data
    18
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 320615 NCBI Gene Model | MGI Sequence Detail 87490 C57BL/6J ±  kb
    transcript NM_177208 RefSeq | MGI Sequence Detail 7908 C57BL/6  
    polypeptide Q8BL99 UniProt | EBI | MGI Sequence Detail 2399 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      cDNA 19
      Primer pair 4

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2444370, MGI:2449769, MGI:6192110
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 10
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory