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Tpd52l1 Gene Detail
Summary
  • Symbol
    Tpd52l1
  • Name
    tumor protein D52-like 1
  • Synonyms
    D53
  • Feature Type
    protein coding gene
  • IDs
    MGI:1298386
    NCBI Gene: 21987
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:31208372-31321954 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 17.36 cM, cytoband A4-B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3994 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1298386
 protein coding gene Chr10:31208369-31321989 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017122
 protein coding gene Chr10:29567331-29677344 (-)
A/J MGP_AJ_G0017099
 protein coding gene Chr10:28699825-28809564 (-)
AKR/J MGP_AKRJ_G0017059
 protein coding gene Chr10:29157286-29269930 (-)
BALB/cJ MGP_BALBcJ_G0017062
 protein coding gene Chr10:28769242-28885660 (-)
C3H/HeJ MGP_C3HHeJ_G0016882
 protein coding gene Chr10:29430018-29545789 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017520
 protein coding gene Chr10:30462287-30575049 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015217
 protein coding gene Chr10:27093559-27195937 (-)
CAST/EiJ MGP_CASTEiJ_G0016461
 protein coding gene Chr10:29493700-29594586 (-)
CBA/J MGP_CBAJ_G0016856
 protein coding gene Chr10:31924635-32051863 (-)
DBA/2J MGP_DBA2J_G0016961
 protein coding gene Chr10:28378298-28497459 (-)
FVB/NJ MGP_FVBNJ_G0016956
 protein coding gene Chr10:27965601-28080712 (-)
LP/J MGP_LPJ_G0017038
 protein coding gene Chr10:29574281-29683615 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016986
 protein coding gene Chr10:32083241-32204545 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017556
 protein coding gene Chr10:29063019-29173570 (-)
PWK/PhJ MGP_PWKPhJ_G0016243
 protein coding gene Chr10:28145251-28259687 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016026
 protein coding gene Chr10:29006402-29117593 (-)
WSB/EiJ MGP_WSBEiJ_G0016524
 protein coding gene Chr10:29208986-29332044 (-)



Homology
more
  • Human Ortholog
    TPD52L1, TPD52 like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TPD52L1, TPD52 like 1
  • Synonyms
    D53, TPD53
  • Links
    NCBI Gene ID: 7164
    neXtProt AC: NX_Q16890
    UniProt: Q16890

  • Chr Location
    6q22.31; chr6:125119049-125264407 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    785
  • Tissues
    16
  • cDNA Data
    37
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000000296 Ensembl Gene Model | MGI Sequence Detail 113583 C57BL/6J ±  kb
    transcript ENSMUST00000213528 Ensembl | MGI Sequence Detail 969 Not Applicable  
    polypeptide ENSMUSP00000149177 Ensembl | MGI Sequence Detail 209 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 40
      Genomic 2
      cDNA 37
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 5
      Gene Ontology 4
      Phenotypes 11
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory