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Syngr2 Gene Detail
Summary
  • Symbol
    Syngr2
  • Name
    synaptogyrin 2
  • Synonyms
    cellugyrin, Clast2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1328324
    NCBI Gene: 20973
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr11:117700494-117705109 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 82.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    169 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1328324
 protein coding gene Chr11:117700459-117705112 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019453
 protein coding gene Chr11:122091704-122096319 (+)
A/J MGP_AJ_G0019421
 protein coding gene Chr11:116680699-116685314 (+)
AKR/J MGP_AKRJ_G0019391
 protein coding gene Chr11:120233043-120237658 (+)
BALB/cJ MGP_BALBcJ_G0019396
 protein coding gene Chr11:117052608-117057207 (+)
C3H/HeJ MGP_C3HHeJ_G0019202
 protein coding gene Chr11:120514647-120519262 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019845
 protein coding gene Chr11:125817903-125822502 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017469
 protein coding gene Chr11:113689488-113694115 (+)
CAST/EiJ MGP_CASTEiJ_G0018755
 protein coding gene Chr11:121943400-121948074 (+)
CBA/J MGP_CBAJ_G0019173
 protein coding gene Chr11:130772087-130776702 (+)
DBA/2J MGP_DBA2J_G0019285
 protein coding gene Chr11:116081778-116086393 (+)
FVB/NJ MGP_FVBNJ_G0019277
 protein coding gene Chr11:115701519-115706118 (+)
LP/J MGP_LPJ_G0019355
 protein coding gene Chr11:122416324-122420939 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019310
 protein coding gene Chr11:129732313-129736903 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019884
 protein coding gene Chr11:120882302-120886917 (+)
PWK/PhJ MGP_PWKPhJ_G0018522
 protein coding gene Chr11:117437542-117442163 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018314
 protein coding gene Chr11:120613722-120618315 (+)
WSB/EiJ MGP_WSBEiJ_G0018808
 protein coding gene Chr11:120849239-120853860 (+)



Homology
more
  • Human Ortholog
    SYNGR2, synaptogyrin 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SYNGR2, synaptogyrin 2
  • Links
    NCBI Gene ID: 9144
    neXtProt AC: NX_O43760
    UniProt: O43760

  • Chr Location
    17q25.3; chr17:78168545-78173527 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    8
  • cDNA Data
    230
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000048277 Ensembl Gene Model | MGI Sequence Detail 4616 C57BL/6J ±  kb
    transcript ENSMUST00000026649 Ensembl | MGI Sequence Detail 1520 Not Applicable  
    polypeptide ENSMUSP00000026649 Ensembl | MGI Sequence Detail 224 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 234
      cDNA 234

      Microarray probesets 4
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 5
    • Earliest
      J:50126 Kedra D, et al., Characterization of the human synaptogyrin gene family. Hum Genet. 1998 Aug;103(2):131-41
    • Latest
      J:234039 Beaton N, et al., TUSC5 regulates insulin-mediated adipose tissue glucose uptake by modulation of GLUT4 recycling. Mol Metab. 2015 Nov;4(11):795-810
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory