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Mycs Gene Detail
Summary
  • Symbol
    Mycs
  • Name
    myc-like oncogene, s-myc protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:1332242
    NCBI Gene: 17870
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    ChrX:5378958-5381319 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 2.40 cM, cytoband A1.2-A2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    71 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1332242
 protein coding gene ChrX:5378952-5381319 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035501
 protein coding gene ChrX:61804-64171 (-)
A/J MGP_AJ_G0035479
 protein coding gene ChrX:57147-59514 (-)
AKR/J MGP_AKRJ_G0035412
 protein coding gene ChrX:61455-63822 (-)
BALB/cJ MGP_BALBcJ_G0035475
 protein coding gene ChrX:58950-61317 (-)
C3H/HeJ MGP_C3HHeJ_G0035182
 protein coding gene ChrX:60260-62627 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035999
 protein coding gene ChrX:52935-55302 (-)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0034483
 protein coding gene ChrX:59524-61895 (-)
CBA/J MGP_CBAJ_G0035152
 protein coding gene ChrX:62050-64417 (-)
DBA/2J MGP_DBA2J_G0035310
 protein coding gene ChrX:54702-57069 (-)
FVB/NJ MGP_FVBNJ_G0035255
 protein coding gene ChrX:61836-64587 (-)
LP/J MGP_LPJ_G0035388
 protein coding gene ChrX:61219-63586 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035295
 protein coding gene ChrX:87663-89853 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036016
 protein coding gene ChrX:51971-54338 (-)
PWK/PhJ MGP_PWKPhJ_G0034185
 protein coding gene ChrX:72488-74857 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034022
 protein coding gene ChrX:56831-59197 (-)
WSB/EiJ MGP_WSBEiJ_G0034606
 protein coding gene ChrX:60776-63143 (-)



Homology
more
  • Human Ortholog
    MYCN, MYCN proto-oncogene, bHLH transcription factor
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYCN, MYCN proto-oncogene, bHLH transcription factor
  • Synonyms
    bHLHe37, FGLDS1, MODED, MPAPA, MYCNsORF, MYCNsPEP, N-myc, NMYC, ODED
  • Links
    NCBI Gene ID: 4613
    neXtProt AC: NX_P04198
    UniProt: P04198

  • Chr Location
    2p24.3; chr2:15940550-15947007 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human MYCN associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    5
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 17870 NCBI Gene Model | MGI Sequence Detail 2362 C57BL/6J ±  kb
transcript NM_010850 RefSeq | MGI Sequence Detail 2362 ZRU/MplStud  
polypeptide Q9Z304 UniProt | EBI | MGI Sequence Detail 431 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    Genomic 4
    cDNA 7
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Developmental Gene Expression 1
    Gene Ontology 5
  • Earliest
    J:52533 Sugiyama A, et al., Molecular cloning and chromosomal mapping of mouse intronless myc gene acting as a potent apoptosis inducer. Gene. 1999 Jan 21;226(2):273-83
  • Latest
    J:215487 Thompson CL, et al., A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory