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Myom1 Gene Detail
Summary
  • Symbol
    Myom1
  • Name
    myomesin 1
  • Synonyms
    D430047A17Rik, skelemin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341430
    NCBI Gene: 17929
  • Alliance
    gene page
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:71326455-71433851 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 41.87 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3992 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341430
 protein coding gene Chr17:71309628-71433851 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024004
 protein coding gene Chr17:73447946-73555935 (+)
A/J MGP_AJ_G0023962
 protein coding gene Chr17:71199395-71325230 (+)
AKR/J MGP_AKRJ_G0023931
 protein coding gene Chr17:72191518-72301141 (+)
BALB/cJ MGP_BALBcJ_G0023963
 protein coding gene Chr17:71126247-71232852 (+)
C3H/HeJ MGP_C3HHeJ_G0023727
 protein coding gene Chr17:73144457-73253447 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024409
 protein coding gene Chr17:76113453-76234861 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021854
 protein coding gene Chr17:66983724-67095761 (+)
CAST/EiJ MGP_CASTEiJ_G0023208
 protein coding gene Chr17:73564769-73677125 (+)
CBA/J MGP_CBAJ_G0023702
 protein coding gene Chr17:79293534-79413358 (+)
DBA/2J MGP_DBA2J_G0023831
 protein coding gene Chr17:69893042-70000400 (+)
FVB/NJ MGP_FVBNJ_G0023797
 protein coding gene Chr17:69359059-69467372 (+)
LP/J MGP_LPJ_G0023913
 protein coding gene Chr17:74200934-74311540 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023825
 protein coding gene Chr17:79173358-79286756 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024453
 protein coding gene Chr17:72702414-72811793 (+)
PWK/PhJ MGP_PWKPhJ_G0022954
 protein coding gene Chr17:69191074-69301634 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022765
 protein coding gene Chr17:69416285-69525999 (+)
WSB/EiJ MGP_WSBEiJ_G0023275
 protein coding gene Chr17:73518310-73631404 (+)



Homology
more
  • Human Ortholog
    MYOM1, myomesin 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MYOM1, myomesin 1
  • Synonyms
    SKELEMIN
  • Links
    NCBI Gene ID: 8736
    neXtProt AC: NX_P52179
    UniProt: P52179

  • Chr Location
    18p11.31; chr18:3066807-3247376 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    14
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    870
  • Tissues
    123
  • cDNA Data
    24
  • Literature Summary
    32
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 17929 NCBI Gene Model | MGI Sequence Detail 107397 C57BL/6J ±  kb
transcript NM_010867 RefSeq | MGI Sequence Detail 5579 C57BL/6  
polypeptide Q62234 UniProt | EBI | MGI Sequence Detail 1667 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    Genomic 6
    cDNA 24
    Primer pair 3
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2444174
References
more
  • Summaries
    All 66
    Developmental Gene Expression 32
    Gene Ontology 14
    Phenotypes 4
  • Earliest
    J:51749 Price MG, et al., Skelemin, a cytoskeletal M-disc periphery protein, contains motifs of adhesion/recognition and intermediate filament proteins. J Biol Chem. 1993 Oct 15;268(29):21800-10
  • Latest
    J:347982 Li C, et al., Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere. J Biol Chem. 2024 Apr 2;300(5):107254
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory