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Atrn Gene Detail
Summary
  • Symbol
    Atrn
  • Name
    attractin
  • Synonyms
    Mgca, mKIAA0548
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341628
    NCBI Gene: 11990
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:130748415-130872253 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 63.26 cM
  • Mapping Data
    19 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2627 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341628
 protein coding gene Chr2:130734363-130872253 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026517
 protein coding gene Chr2:134398656-134529787 (+)
A/J MGP_AJ_G0026481
 protein coding gene Chr2:128953705-129077398 (+)
AKR/J MGP_AKRJ_G0026456
 protein coding gene Chr2:132674212-132811687 (+)
BALB/cJ MGP_BALBcJ_G0026493
 protein coding gene Chr2:129324400-129465367 (+)
C3H/HeJ MGP_C3HHeJ_G0026236
 protein coding gene Chr2:133111570-133238526 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026938
 protein coding gene Chr2:138544942-138674343 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024315
 protein coding gene Chr2:123694049-123816111 (+)
CAST/EiJ MGP_CASTEiJ_G0025697
 protein coding gene Chr2:133381643-133513019 (+)
CBA/J MGP_CBAJ_G0026216
 protein coding gene Chr2:143697160-143825068 (+)
DBA/2J MGP_DBA2J_G0026350
 protein coding gene Chr2:128338936-128462999 (+)
FVB/NJ MGP_FVBNJ_G0026314
 protein coding gene Chr2:126974191-127098232 (+)
LP/J MGP_LPJ_G0026455
 protein coding gene Chr2:134640165-134772535 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026334
 protein coding gene Chr2:147514890-147647986 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026993
 protein coding gene Chr2:132633706-132762255 (+)
PWK/PhJ MGP_PWKPhJ_G0025433
 protein coding gene Chr2:127905079-128031830 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025235
 protein coding gene Chr2:131783879-131913533 (+)
WSB/EiJ MGP_WSBEiJ_G0025771
 protein coding gene Chr2:133558164-133686320 (+)



Homology
more
  • Human Ortholog
    ATRN, attractin
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATRN, attractin
  • Synonyms
    DPPT-L, MGCA
  • Links
    NCBI Gene ID: 8455
    neXtProt AC: NX_O75882
    UniProt: O75882

  • Chr Location
    20p13; chr20:3471018-3651118 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotypes from 6 alleles in 11 genetic backgrounds
    6 phenotypes from multigenic genotypes
    39 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Some mutant homozygotes exhibit decreases in phaeomelanin synthesis, body weight, and adiposity; increases in locomotion, and abnormal myelination and vacuolation of the central nervous system resulting in tremors.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    909
  • Tissues
    58
  • cDNA Data
    115
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027312 Ensembl Gene Model | MGI Sequence Detail 123839 C57BL/6J ±  kb
    transcript ENSMUST00000028781 Ensembl | MGI Sequence Detail 8745 Not Applicable  
    polypeptide ENSMUSP00000028781 Ensembl | MGI Sequence Detail 1428 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 132
      Genomic 15
      cDNA 116
      Primer pair 1

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGD-MRK-12216, MGI:2139403, MGI:96972
    References
    more
    • Summaries
      All 75
      Developmental Gene Expression 6
      Gene Ontology 10
      Phenotypes 39
    • Earliest
      J:103 Lane PW, et al., Mahogany, a recessive color mutation in linkage group V of the mouse. J Hered. 1960;51(5):228-230
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory