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Trank1 Gene Detail
Summary
  • Symbol
    Trank1
  • Name
    tetratricopeptide repeat and ankyrin repeat containing 1
  • Synonyms
    A230061D21Rik, C030048J01Rik, Lba1, LOC235639
  • Feature Type
    protein coding gene
  • IDs
    MGI:1341834
    NCBI Gene: 320429
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:111140807-111224843 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 60.95 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2066 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1341834
 protein coding gene Chr9:111140351-111224843 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035373
 protein coding gene Chr9:113546655-113632605 (+)
A/J MGP_AJ_G0035354
 protein coding gene Chr9:109388141-109470758 (+)
AKR/J MGP_AKRJ_G0035285
 protein coding gene Chr9:112117613-112202537 (+)
BALB/cJ MGP_BALBcJ_G0035349
 protein coding gene Chr9:109138059-109220953 (+)
C3H/HeJ MGP_C3HHeJ_G0035057
 protein coding gene Chr9:112619809-112705532 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035871
 protein coding gene Chr9:116656480-116742134 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032757
 protein coding gene Chr9:106588398-106672535 (+)
CAST/EiJ MGP_CASTEiJ_G0034363
 protein coding gene Chr9:112419704-112519704 (+)
CBA/J MGP_CBAJ_G0035024
 protein coding gene Chr9:120965123-121058571 (+)
DBA/2J MGP_DBA2J_G0035183
 protein coding gene Chr9:108836114-108918407 (+)
FVB/NJ MGP_FVBNJ_G0035130
 protein coding gene Chr9:107676025-107757503 (+)
LP/J MGP_LPJ_G0035262
 protein coding gene Chr9:113818572-113906361 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035170
 protein coding gene Chr9:122258951-122357708 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035891
 protein coding gene Chr9:112468758-112555824 (+)
PWK/PhJ MGP_PWKPhJ_G0034070
 protein coding gene Chr9:109091188-109175530 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033905
 protein coding gene Chr9:112561510-112653944 (+)
WSB/EiJ MGP_WSBEiJ_G0034484
 protein coding gene Chr9:112327568-112411793 (+)



Homology
more
  • Human Ortholog
    TRANK1, tetratricopeptide repeat and ankyrin repeat containing 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRANK1, tetratricopeptide repeat and ankyrin repeat containing 1
  • Synonyms
    LBA1
  • Links
    NCBI Gene ID: 9881
    neXtProt AC: NX_O15050
    UniProt: O15050

  • Chr Location
    3p22.2; chr3:36826819-36945744 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display reduced anxiety-like behavior and nocturnal hypolocomotion.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    954
  • Tissues
    19
  • cDNA Data
    55
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000062296 Ensembl Gene Model | MGI Sequence Detail 84037 C57BL/6J ±  kb
    transcript ENSMUST00000078626 Ensembl | MGI Sequence Detail 10520 Not Applicable  
    polypeptide ENSMUSP00000077697 Ensembl | MGI Sequence Detail 2999 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 55
      cDNA 55

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:1924728, MGI:2444004, MGI:2685033
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 3
      Phenotypes 8
    • Earliest
      J:48894 Moore PM, et al., Identification and cloning of a brain autoantigen in neuro-behavioral SLE. J Neuroimmunol. 1998 Mar 1;82(2):116-25
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory