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Mmp23 Gene Detail
Summary
  • Symbol
    Mmp23
  • Name
    matrix metallopeptidase 23
  • Synonyms
    CA-MMP, cysteine array matrix metalloproteinase
  • Feature Type
    protein coding gene
  • IDs
    MGI:1347361
    NCBI Gene: 26561
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:155735112-155737841 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 86.85 cM, cytoband E2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    201 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1347361
 protein coding gene Chr4:155735111-155738982 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029220
 protein coding gene Chr4:160000045-160002774 (-)
A/J MGP_AJ_G0029185
 protein coding gene Chr4:153272445-153275174 (-)
AKR/J MGP_AKRJ_G0029133
 protein coding gene Chr4:157438374-157441103 (-)
BALB/cJ MGP_BALBcJ_G0029201
 protein coding gene Chr4:153743693-153746422 (-)
C3H/HeJ MGP_C3HHeJ_G0028922
 protein coding gene Chr4:157984030-157986759 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029650
 protein coding gene Chr4:165682553-165685282 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026895
 protein coding gene Chr4:145561821-145564543 (-)
CAST/EiJ MGP_CASTEiJ_G0028334
 protein coding gene Chr4:155439792-155442511 (-)
CBA/J MGP_CBAJ_G0028884
 protein coding gene Chr4:170687304-170690033 (-)
DBA/2J MGP_DBA2J_G0029033
 protein coding gene Chr4:153292144-153294873 (-)
FVB/NJ MGP_FVBNJ_G0028996
 protein coding gene Chr4:152531912-152534640 (-)
LP/J MGP_LPJ_G0029123
 protein coding gene Chr4:159917114-159919843 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029023
 protein coding gene Chr4:173499835-173502563 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029682
 protein coding gene Chr4:158065134-158067863 (-)
PWK/PhJ MGP_PWKPhJ_G0028055
 protein coding gene Chr4:149432440-149435166 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027889
 protein coding gene Chr4:152323929-152326591 (-)
WSB/EiJ MGP_WSBEiJ_G0028414
 protein coding gene Chr4:158235492-158238220 (-)



Homology
more
  • Human Ortholog
    MMP23B, matrix metallopeptidase 23B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MMP23B, matrix metallopeptidase 23B
  • Synonyms
    MIFR, MIFR-1, MMP22, MMP23A
  • Links
    NCBI Gene ID: 8510
    neXtProt AC: NX_O75900
    UniProt: O75900

  • Chr Location
    1p36.33; chr1:1632163-1635263 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    761
  • Tissues
    22
  • cDNA Data
    19
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029061 Ensembl Gene Model | MGI Sequence Detail 2730 C57BL/6J ±  kb
transcript ENSMUST00000030937 Ensembl | MGI Sequence Detail 1434 Not Applicable  
polypeptide ENSMUSP00000030937 Ensembl | MGI Sequence Detail 391 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    Genomic 1
    cDNA 19
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:57238 Pei D, CA-MMP: a matrix metalloproteinase with a novel cysteine array, but without the classic cysteine switch. FEBS Lett. 1999 Aug 27;457(2):262-70
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory