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Tspan32 Gene Detail
Summary
  • Symbol
    Tspan32
  • Name
    tetraspanin 32
  • Synonyms
    Art-1, D7Wsu37e, Phemx, Tspan32, Tssc6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1350360
    NCBI Gene: 27027
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:142558644-142573223 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 88.09 cM
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    325 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1350360
 protein coding gene Chr7:142558644-142573381 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033267
 protein coding gene Chr7:148286069-148300561 (+)
A/J MGP_AJ_G0033250
 protein coding gene Chr7:143986348-144001818 (+)
AKR/J MGP_AKRJ_G0033181
 protein coding gene Chr7:148031534-148046914 (+)
BALB/cJ MGP_BALBcJ_G0033250
 protein coding gene Chr7:143761947-143776658 (+)
C3H/HeJ MGP_C3HHeJ_G0032966
 protein coding gene Chr7:147800241-147814792 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033760
 protein coding gene Chr7:153649771-153664333 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030733
 protein coding gene Chr7:145197822-145212735 (+)
CAST/EiJ MGP_CASTEiJ_G0032288
 protein coding gene Chr7:140099473-140113999 (+)
CBA/J MGP_CBAJ_G0032937
 protein coding gene Chr7:158909462-158923961 (+)
DBA/2J MGP_DBA2J_G0033091
 protein coding gene Chr7:141961585-141976142 (+)
FVB/NJ MGP_FVBNJ_G0033039
 protein coding gene Chr7:141882201-141896768 (+)
LP/J MGP_LPJ_G0033183
 protein coding gene Chr7:149804534-149819410 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033073
 protein coding gene Chr7:159504769-159519329 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033780
 protein coding gene Chr7:146999870-147015496 (+)
PWK/PhJ MGP_PWKPhJ_G0031997
 protein coding gene Chr7:135262506-135277592 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031843
 protein coding gene Chr7:133804710-133820833 (+)
WSB/EiJ MGP_WSBEiJ_G0032400
 protein coding gene Chr7:148001407-148016004 (+)



Homology
more
  • Human Ortholog
    TSPAN32, tetraspanin 32
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TSPAN32, tetraspanin 32
  • Synonyms
    ART1, PHEMX, PHMX, TSSC6
  • Links
    NCBI Gene ID: 10077
    neXtProt AC: NX_Q96QS1
    UniProt: Q96QS1

  • Chr Location
    11p15.5; chr11:2301997-2318204 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 2 alleles in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trap null mutation exhibit normal hematopoiesis, hemolytic and granulopoitic responses. B cells exhibit normal proliferative responses while T cells demonstrate enhanced proliferation upon T cell receptor stimulation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    817
  • Tissues
    34
  • cDNA Data
    29
  • Literature Summary
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 27027 NCBI Gene Model | MGI Sequence Detail 14580 C57BL/6J ±  kb
    transcript NM_020286 RefSeq | MGI Sequence Detail 1697 ZRU/MplStud  
    polypeptide Q9JHH2 UniProt | EBI | MGI Sequence Detail 256 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 33
      cDNA 30
      Primer pair 3

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGD-MRK-34140, MGI:106446, MGI:1861715, MGI:2142216, MGI:2142302
    References
    more
    • Summaries
      All 49
      Developmental Gene Expression 10
      Gene Ontology 4
      Phenotypes 12
    • Earliest
      J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory