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Pdlim4 Gene Detail
Summary
  • Symbol
    Pdlim4
  • Name
    PDZ and LIM domain 4
  • Synonyms
    Ril
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353470
    NCBI Gene: 30794
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:53945754-53959814 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 32.13 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    404 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353470
 protein coding gene Chr11:53945754-53959840 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018310
 protein coding gene Chr11:53514663-53528738 (-)
A/J MGP_AJ_G0018279
 protein coding gene Chr11:51513997-51528061 (-)
AKR/J MGP_AKRJ_G0018248
 protein coding gene Chr11:53202651-53216705 (-)
BALB/cJ MGP_BALBcJ_G0018250
 protein coding gene Chr11:51852834-51866893 (-)
C3H/HeJ MGP_C3HHeJ_G0018061
 protein coding gene Chr11:53143300-53157361 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018702
 protein coding gene Chr11:55162951-55176998 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016352
 protein coding gene Chr11:48982508-48996706 (-)
CAST/EiJ MGP_CASTEiJ_G0017626
 protein coding gene Chr11:53188872-53202885 (-)
CBA/J MGP_CBAJ_G0018036
 protein coding gene Chr11:57777754-57791819 (-)
DBA/2J MGP_DBA2J_G0018145
 protein coding gene Chr11:51233043-51247185 (-)
FVB/NJ MGP_FVBNJ_G0018137
 protein coding gene Chr11:50874029-50890293 (-)
LP/J MGP_LPJ_G0018220
 protein coding gene Chr11:53964190-53978256 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018163
 protein coding gene Chr11:59004589-59018664 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018744
 protein coding gene Chr11:53214042-53228143 (-)
PWK/PhJ MGP_PWKPhJ_G0017399
 protein coding gene Chr11:51770010-51784136 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017194
 protein coding gene Chr11:52984268-52998253 (-)
WSB/EiJ MGP_WSBEiJ_G0017674
 protein coding gene Chr11:52856301-52870446 (-)



Homology
more
  • Human Ortholog
    PDLIM4, PDZ and LIM domain 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PDLIM4, PDZ and LIM domain 4
  • Synonyms
    RIL
  • Links
    NCBI Gene ID: 8572
    neXtProt AC: NX_P50479
    UniProt: P50479

  • Chr Location
    5q31.1; chr5:132257696-132273454 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PDLIM4 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    51
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1034
  • Tissues
    118
  • cDNA Data
    41
  • Literature Summary
    15
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 30794 NCBI Gene Model | MGI Sequence Detail 14061 C57BL/6J ±  kb
    transcript NM_019417 RefSeq | MGI Sequence Detail 1156 C57BL/6  
    polypeptide P70271 UniProt | EBI | MGI Sequence Detail 330 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 44
      Genomic 2
      cDNA 41
      Primer pair 1

      Microarray probesets 4
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 15
      Gene Ontology 9
      Phenotypes 11
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory