a<x> Radiation induced Allele Detail MGI Mouse (MGI:1855944)

a^x
Radiation induced Allele Detail

Summary

Symbol:	a^x
Name:	nonagouti; lethal nonagouti
MGI ID:	MGI:1855944
Synonyms:	a(x)
Gene:	a Location: Chr2:154792519-154892932 bp, + strand Genetic Position: Chr2, 76.83 cM
Alliance:	a^x page

Mutation
origin

Strain of Origin:

(C3H/Rl x 101/Rl)F1

Mutation
description

Allele Type:		Radiation induced
Mutation:		Intergenic deletion
		Mutation details: This allele comprises a deletion of approximately 100 kb, which does not affect agouti coding sequences, but begins 4 kb 3' of the last exon, and thus may affect coat color by removing an agouti 3' enhancer. The Ahcy gene, which codes for the enzyme S-adenosylhomocysteine hydrolase (SAHase), is contained within a 20 kb region within the a(x) deletion. (J:17867)
Inheritance:		Other (see notes)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	5 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any a Mutation:	463 strains or lines available

Notes

a^x is recessive to A^y, A^w, A, and a^t, and dominant to a.

References

Original:	J:174047 Russell LB, et al., Crossing over within the a "locus" of the mouse. Genetics. 1963;48:907 Abstr
All:	7 reference(s)

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