Tyrp1<B-lt> Spontaneous Allele Detail MGI Mouse (MGI:1855962)

Tyrp1^B-lt
Spontaneous Allele Detail

Summary

Symbol:	Tyrp1^B-lt
Name:	tyrosinase-related protein 1; light
MGI ID:	MGI:1855962
Gene:	Tyrp1 Location: Chr4:80752360-80769956 bp, + strand Genetic Position: Chr4, 37.89 cM
Alliance:	Tyrp1^B-lt page

Tyrp1^B-lt/Tyrp1^B-lt

Show the 1 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:

C58

Mutation
description

Allele Type:		Spontaneous
Mutation:		Single point mutation
		Mutation details: A C-to-T transition at coding nucleotide 112 is predicted to result in an arginine to cysteine substitition at codon 38 (p.R38C). (J:1086)
Inheritance:		Semidominant

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available Cell Lines: 0 lines available
Carrying any Tyrp1 Mutation:	162 strains or lines available

References

Original:	J:13061 MacDOWELL EC, 'Light'--a new mouse color. J Hered. 1950 Feb;41(2):35-6
All:	18 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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