Tyr<c-p> Spontaneous Allele Detail MGI Mouse (MGI:1855981)

Tyr^c-p
Spontaneous Allele Detail

Summary

Symbol:	Tyr^c-p
Name:	tyrosinase; platinum
MGI ID:	MGI:1855981
Synonyms:	c^P
Gene:	Tyr Location: Chr7:87073979-87142637 bp, - strand Genetic Position: Chr7, 49.01 cM
Alliance:	Tyr^c-p page

Mutation
origin

Strain of Origin:

DBA/2J

Mutation
description

Allele Type:		Spontaneous
Mutation:		Single point mutation
		Mutation details: The mutation in the platinum allele was found to be an A-to-T substitution, changing a lysine residue at position 507 or 489 to a termination codon (p.K507* for pre-protein, p.K489* for mature protein). (J:30177)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Tyr Mutation:	379 strains or lines available

References

Original:	J:13442 Dickie MM, Platinum. Mouse News Lett. 1966;34:30
All:	6 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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