Myo5a<d> Spontaneous Allele Detail MGI Mouse (MGI:1856004)

Myo5a^d
Spontaneous Allele Detail

Summary

Symbol:	Myo5a^d
Name:	myosin VA; dilute
MGI ID:	MGI:1856004
Synonyms:	blue dilution, d, d^v, Maltese dilution
Gene:	Myo5a Location: Chr9:74978297-75130970 bp, + strand Genetic Position: Chr9, 42.26 cM
Alliance:	Myo5a^d page

A homozygous a/a Myo5a^d/ Myo5a^d mouse with wild-type nonagouti black sibling

Show the 5 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:

old mutant of the mouse fancy

Mutation
description

Allele Type:		Spontaneous
Mutation:		Viral insertion
		Mutation details: This mutation is the result of the integration of ecotropic murine leukemia virus Emv-3 into a noncoding region of the Myo5a^d gene. Reversions of Myo5a^d to wild-type are caused by excision of the virus leaving exactly one long terminal repeat in place. (J:6587, J:7092, J:7751)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Tumor Data

List all tumor models in MMHCdb carrying Myo5a^d

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 105 strains available Cell Lines: 0 lines available
Carrying any Myo5a Mutation:	265 strains or lines available

References

Original:	J:12958 Russell ES, A Quantitative Histological Study of the Pigment Found in the Coat-Color Mutants of the House Mouse. IV. the Nature of the Effects of Genic Substitution in Five Major Allelic Series. Genetics. 1949 Mar;34(2):146-66
All:	38 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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