Myo5a<d-l> Spontaneous Allele Detail MGI Mouse (MGI:1856005)

Myo5a^d-l
Spontaneous Allele Detail

Summary

Symbol:	Myo5a^d-l
Name:	myosin VA; dilute lethal
MGI ID:	MGI:1856005
Synonyms:	d^l
Gene:	Myo5a Location: Chr9:74978297-75130970 bp, + strand Genetic Position: Chr9, 42.26 cM
Alliance:	Myo5a^d-l page

Mutation
origin

Strain of Origin:

C57BL/Gr

Mutation
description

Allele Type:		Spontaneous
Mutation:		Undefined
		This Myo5a allele was identifed by a noncomlementation test result with Myo5a^d. (J:12978)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available Cell Lines: 0 lines available
Carrying any Myo5a Mutation:	265 strains or lines available

Notes

Myo5a^d-l, dilute-lethal, recessive. Dilute-lethal arose in the C57BL/Gr strain. The color of Myo5a^d-l homozygotes is identical to that of Myo5a^d homozygotes, but dilute-lethal mice develop a severe neuromuscular disorder characterized by convulsions and opisthotonus (arching upward of the head and tail), and they usually die at about 3 weeks of age (J:12978).

References

Original:	J:24768 Searle AG, New mutant, allele of Maltese dilution, d. Mouse News Lett. 1951;4:10
All:	21 reference(s)

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