Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | Notes | References

Symbol: Lama2dy Name: laminin, alpha 2; dystrophia muscularis MGI ID: MGI:1856026 Synonyms: dy Gene: Lama2  Location: Chr10:26857281-27493021 bp, - strand  Genetic Position: Chr10, 14.23 cM, cytoband A4-B1 Alliance: Lama2dy page

Lama2dy/Lama2dy and control Show the 1 phenotype image(s) involving this allele.

Strain of Origin:

129P1/Re

Allele Type:    Spontaneous Mutation:    Undefined   Mutation details: Analysis of Lama2 expression of dystrophic dy mice revealed a specific deficiency of this mRNA in skeletal muscle, cardiac muscle, and peripheral nerve. (J:18187, J:44989) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	9 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	15 anatomical structure(s)

List all tumor models in MMHCdb carrying Lama2dy

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Lama2 Mutation:	177 strains or lines available

Original:	J:13125 Michelson AM, et al., Dystrophia muscularis: a hereditary primary myopathy in the house mouse. Proc Natl Acad Sci U S A. 1955 Dec 15;41(12):1079-1084
All:	77 reference(s)