Mc1r<E-so> Spontaneous Allele Detail MGI Mouse (MGI:1856029)

Mc1r^E-so
Spontaneous Allele Detail

Summary

Symbol:	Mc1r^E-so
Name:	melanocortin 1 receptor; sombre
MGI ID:	MGI:1856029
Synonyms:	E^so, So
Gene:	Mc1r Location: Chr8:124133846-124137483 bp, + strand Genetic Position: Chr8, 72.1 cM
Alliance:	Mc1r^E-so page

Mutation
origin

Strain of Origin:

C3H

Mutation
description

Allele Type:		Spontaneous
Mutation:		Single point mutation
		Mutation details: A T-to-C mutation in codon 98 is predicted to result in a leucine to proline alteration at this position (p.L98P). (J:4636)
Inheritance:		Semidominant

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available Cell Lines: 0 lines available
Carrying any Mc1r Mutation:	44 strains or lines available

References

Original:	J:13077 Bateman N, Sombre, a viable dominant mutant in the house mouse. J Hered. 1961;52(4):186-189
All:	6 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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