Sgk3<fz> Spontaneous Allele Detail MGI Mouse (MGI:1856038)

Sgk3^fz
Spontaneous Allele Detail

Summary

Symbol:	Sgk3^fz
Name:	serum/glucocorticoid regulated kinase 3; fuzzy
MGI ID:	MGI:1856038
Gene:	Sgk3 Location: Chr1:9868332-9971070 bp, + strand Genetic Position: Chr1, 2.08 cM
Alliance:	Sgk3^fz page

Mutation
origin

Strain of Origin:

CFW stock

Mutation
description

Allele Type:		Spontaneous
Mutation:		Insertion
		Mutation details: This mutation comprises insertion of a single adenine following nucleotide 579 of the cDNA sequence, in a region encoded by exon 10 of the gene, that causes a shift in the amino acid reading frame and premature termination of protein translation following leucine 192 (Leu192Ter), which resides in the serine/threonine kinase domain. (J:125551)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available Cell Lines: 0 lines available
Carrying any Sgk3 Mutation:	30 strains or lines available

References

Original:	J:90 DICKIE MM, et al., Fuzzy mice. J Hered. 1950 Jul;41(7):193-6
All:	10 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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