Hr<hr> Spontaneous Allele Detail MGI Mouse (MGI:1856057)

Hr^hr
Spontaneous Allele Detail

Summary

Symbol:	Hr^hr
Name:	lysine demethylase and nuclear receptor corepressor; hairless
MGI ID:	MGI:1856057
Synonyms:	hr, SKH-1
Gene:	Hr Location: Chr14:70789652-70810988 bp, + strand Genetic Position: Chr14, 36.32 cM
Alliance:	Hr^hr page

Hr^hr/Hr^hr mouse

Show the 3 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:

Not Specified

Mutation
description

Allele Type:		Spontaneous
Mutation:		Viral insertion
		Mutation details: The hr allele is the result of a retroviral integration. Insertion of murine leukemia proviral sequences into intron 6 results in aberrant splicing of the gene. (J:9252, J:19624, J:92053)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	2 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	9 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Hr^hr

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 18 strains available Cell Lines: 0 lines available
Carrying any Hr Mutation:	87 strains or lines available

References

Original:	J:2405 Brooke HC, Hairless mice. J Hered. 1926;17(5):173-74
All:	125 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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