Lbr<ic> Spontaneous Allele Detail MGI Mouse (MGI:1856063)

Lbr^ic
Spontaneous Allele Detail

Summary

Symbol:	Lbr^ic
Name:	lamin B receptor; ichthyosis
MGI ID:	MGI:1856063
Synonyms:	ic
Gene:	Lbr Location: Chr1:181642880-181669933 bp, - strand Genetic Position: Chr1, 84.89 cM
Alliance:	Lbr^ic page

Mutation
origin

Strain of Origin:

Not Specified

Mutation
description

Allele Type:		Spontaneous
Mutation:		Single point mutation
		Mutation details: A spontaneous mutation that arose in a sib-mated stock at Edinburgh in 1948. The mutation in the ic mouse was identified as a transition (523C>T) that introduces a premature stop codon at the glutamine codon at position 175 (p.Q175*).
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Tumor Data

List all tumor models in MMHCdb carrying Lbr^ic

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Lbr Mutation:	57 strains or lines available

References

Original:	J:64274 Carter TC, et al., ic - ichthyosis. Mouse News Lett. 1949;1S:1
All:	14 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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