Cdh23<v-df> Spontaneous Allele Detail MGI Mouse (MGI:1856229)

Cdh23^v-df
Spontaneous Allele Detail

Summary

Symbol:	Cdh23^v-df
Name:	cadherin related 23 (otocadherin); deaf
MGI ID:	MGI:1856229
Gene:	Cdh23 Location: Chr10:60138527-60532269 bp, - strand Genetic Position: Chr10, 30.11 cM
Alliance:	Cdh23^v-df page

Mutation
origin

Strain of Origin:

Mutation
description

Allele Type:		Spontaneous
Inheritance:		Recessive

Phenotypes

Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

	Allelic Composition	Genetic Background	Cell Line(s)
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hm1	Cdh23^v-df/Cdh23^v-df	Not Specified

Phenotypes:

Affected Systems	hm1
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behavior/neurological	√
abnormal motor capabilities/coordination/movement	√
absent pinna reflex	√
craniofacial	√
abnormal ear position	√
growth/size/body	√
abnormal ear position	√
hearing/vestibular/ear	√
abnormal ear position	√
organ of Corti degeneration	√
abnormal stria vascularis morphology	√
deafness	√
nervous system	√
abnormal cochlear ganglion morphology	√

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Cdh23 Mutation:	281 strains or lines available

References

Original:	J:12997 Deol MS, A gene for uncomplicated deafness in the mouse. J Embryol Exp Morphol. 1956;4(2):190-195
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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