Tgm3<we> Spontaneous Allele Detail MGI Mouse (MGI:1856269)

Tgm3^we
Spontaneous Allele Detail

Summary

Symbol:	Tgm3^we
Name:	transglutaminase 3, E polypeptide; wellhaarig
MGI ID:	MGI:1856269
Gene:	Tgm3 Location: Chr2:129854269-129892319 bp, + strand Genetic Position: Chr2, 63.19 cM
Alliance:	Tgm3^we page

Mutation
origin

Strain of Origin:

Agnes Bluhm's stocks

Mutation
description

Allele Type:		Spontaneous
Mutation:		Single point mutation
		Mutation details: A spontaneous C-to-T point mutation in exon 13 results in premature termination codon at arginine 658 (p.R658) and the loss of the last 36 amino acids. There is also an insertion/duplication of AGTC in intron 12 between position chr2:130048178-130048179 (GRCm38) (duplication of 130048179-130048182). (J:225940*)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 6 strains available Cell Lines: 0 lines available
Carrying any Tgm3 Mutation:	55 strains or lines available

References

Original:	J:208 Hertwig P, Neue Mutationen und Koppelungsgruppen bei der Hausmaus. Z Indukt Abstamm Vererbungsl. 1942;80(1):220-246
All:	11 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24