Fgf5<go> Spontaneous Allele Detail MGI Mouse (MGI:1856336)

Fgf5^go
Spontaneous Allele Detail

Summary

Symbol:	Fgf5^go
Name:	fibroblast growth factor 5; angora
MGI ID:	MGI:1856336
Synonyms:	FGF-5-, go
Gene:	Fgf5 Location: Chr5:98402108-98424892 bp, + strand Genetic Position: Chr5, 47.77 cM, cytoband E1-F
Alliance:	Fgf5^go page

Mutation
origin

Strain of Origin:

BALB/cJ

Mutation
description

Allele Type:		Spontaneous
Mutation:		Intragenic deletion
		Mutation details: Sequences encoding exon 1 are deleted in this mutation. The deletion extends at least 2 kb 5' to the translation start site. Expression of Fgf5 in hair follicles of wild-type mice is localized to the outer root sheath during the hair production phase of the follicle cycle. FGF5 may function as an inhibitor of hair elongation. (J:20551)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available Cell Lines: 0 lines available
Carrying any Fgf5 Mutation:	15 strains or lines available

References

Original:	J:13413 Dickie MM, Angora. Mouse News Lett. 1963;29:39
All:	10 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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