Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Spta1sph
Name:	spectrin alpha, erythrocytic 1; spherocytosis
MGI ID:	MGI:1856377
Synonyms:	sph
Gene:	Spta1  Location: Chr1:174000342-174076016 bp, + strand  Genetic Position: Chr1, 80.97 cM
Alliance:	Spta1sph page

Strain of Origin:

C3H

Allele Type:    Spontaneous Mutation:    Intragenic deletion   Mutation details: The mutation in the sph mouse was identified as a single base pair deletion in exon 11 that causes a frame shift and premature stop codon. (J:80999) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Spta1 Mutation:	147 strains or lines available

Original:	J:12276 JOE M, et al., A new mutation (sph) causing neonatal jaundice in the house mouse. Can J Genet Cytol. 1962 Jun;4:219-25
All:	23 reference(s)