Lmx1a<dr> Spontaneous Allele Detail MGI Mouse (MGI:1856494)

Lmx1a^dr
Spontaneous Allele Detail

Summary

Symbol:	Lmx1a^dr
Name:	LIM homeobox transcription factor 1 alpha; dreher
MGI ID:	MGI:1856494
Synonyms:	dr
Gene:	Lmx1a Location: Chr1:167516806-167676310 bp, + strand Genetic Position: Chr1, 75.08 cM
Alliance:	Lmx1a^dr page

Mutation
origin

Strain of Origin:

wild

Mutation
description

Allele Type:		Spontaneous
Mutation:		Single point mutation
		Mutation details: An A-to-T transversion in exon 2 resulted in an aspartate to valine substitution at amino acid 44 (p.D44V). (J:115043)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	149 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Lmx1a Mutation:	21 strains or lines available

Notes

This allele was discovered in a litter of wild mice captured in a factory in Detmold Germany.

References

Original:	J:15346 FALCONER DS, et al., [Dreher, a new gene of the waltzer-shaker group in the house mouse.]. Z Indukt Abstamm Vererbungsl. 1951;84(2):71-3
All:	13 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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