Slc45a2<uw> Spontaneous Allele Detail MGI Mouse (MGI:1856581)

Slc45a2^uw
Spontaneous Allele Detail

Summary

Symbol:	Slc45a2^uw
Name:	solute carrier family 45, member 2; underwhite
MGI ID:	MGI:1856581
Synonyms:	uw
Gene:	Slc45a2 Location: Chr15:11000807-11029319 bp, + strand Genetic Position: Chr15, 5.4 cM
Alliance:	Slc45a2^uw page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:		Spontaneous
Mutation:		Intragenic deletion
		Mutation details: Molecular analysis reveals a 7 bp deletion in Exon 3, which results in a 43 amino acid frameshift followed by a premature stop at codon 308. The resulting protein lacks the C terminal 6 transmembrane domains. (J:73642)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available Cell Lines: 0 lines available
Carrying any Slc45a2 Mutation:	55 strains or lines available

References

Original:	J:13420 Dickie MM, Underwhite. Mouse News Lett. 1964;30:30
All:	9 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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