Cdk5rap2<an> Radiation induced Allele Detail MGI Mouse (MGI:1856646)

Cdk5rap2^an
Radiation induced Allele Detail

Summary

Symbol:	Cdk5rap2^an
Name:	CDK5 regulatory subunit associated protein 2; Hertwig's anemia
MGI ID:	MGI:1856646
Gene:	Cdk5rap2 Location: Chr4:70135092-70328672 bp, - strand Genetic Position: Chr4, 35.92 cM, cytoband C2
Alliance:	Cdk5rap2^an page

Mutation
origin

Strain of Origin:

Not Specified

Mutation
description

Allele Type:		Radiation induced (Modified isoform(s))
Mutations:		Intragenic deletion, Inversion
		Mutation details: Exon 4 is inverted which results in an in-frame 111 bp deletion with the loss of exon 4 from the mRNA. Northern analysis demonstrated that exon 4 was uniformly omitted from the mutant mRNA. (J:160533)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available Cell Lines: 0 lines available
Carrying any Cdk5rap2 Mutation:	87 strains or lines available

References

Original:	J:208 Hertwig P, Neue Mutationen und Koppelungsgruppen bei der Hausmaus. Z Indukt Abstamm Vererbungsl. 1942;80(1):220-246
All:	21 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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