Ostm1<gl> Spontaneous Allele Detail MGI Mouse (MGI:1856885)

Ostm1^gl
Spontaneous Allele Detail

Summary

Symbol:	Ostm1^gl
Name:	osteopetrosis associated transmembrane protein 1; grey-lethal
MGI ID:	MGI:1856885
Synonyms:	gl, grey lethal
Gene:	Ostm1 Location: Chr10:42554912-42578458 bp, + strand Genetic Position: Chr10, 22.89 cM
Alliance:	Ostm1^gl page

Ostm1^gl/Ostm1^gl and control

Show the 1 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:

STOCK Tyr^c-e

Mutation
description

Allele Type:		Spontaneous
Mutations:		Intragenic deletion, Transposon insertion
		Mutation details: The mutation in the grey lethal mouse was identified as a genomic deletion of the 5' region of the gene. The deletion spanned 7.5 kb and included the promoter, the first exon and part of the first intron. The genomic sequence also included 460 bp corresponding to the 3' UTR of a LINE1 element at the deletion breakpoints. (J:82658)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Mice Carrying this Mutation:	12 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	9 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Ostm1 Mutation:	23 strains or lines available

References

Original:	J:15551 Gruneberg H, A new sub-lethal colour mutation in the house mouse. Proc R Soc Lond B Biol Sci. 1935;118:321-42
All:	25 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24