Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Pdss2kd
Name:	prenyl (solanesyl) diphosphate synthase, subunit 2; kidney disease
MGI ID:	MGI:1856927
Synonyms:	kd
Gene:	Pdss2  Location: Chr10:43097482-43340878 bp, + strand  Genetic Position: Chr10, 22.91 cM, cytoband B2
Alliance:	Pdss2kd page

Strain of Origin:

CBA/H

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: A G-to-A transition mutation occured in codon 117 resulting in a valine to methionine substitution in the encoded protein (p.V117M). The mutation is contained in both alternative splice products. (J:65389, J:101779) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pdss2 Mutation:	31 strains or lines available

Original:	J:24778 Hulse EV, et al., Kidney disease, kd. Mouse News Lett. 1965;32:38
All:	19 reference(s)