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Rorasg
Spontaneous Allele Detail
Summary
Symbol: Rorasg
Name: RAR-related orphan receptor alpha; staggerer
MGI ID: MGI:1857035
Synonyms: RORalpha-, sg
Gene: Rora  Location: Chr9:68561068-69295528 bp, + strand  Genetic Position: Chr9, 37.45 cM
Alliance: Rorasg page
Mutation
origin
Strain of Origin:  obese stock
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation details: This allele contains a 6.5kb genomic deletion of an exon encoding part of the ligand binding domain. The deletion results in an exon-skipping event that introduces a shift in the reading frame. The resulting protein is predicted to be truncated due to introduction of a premature stop codon. (J:31470)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 73 assay results
2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 29 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Rora Mutation:  43 strains or lines available
References
Original:  J:13140 SIDMAN RL, et al., Staggerer, a new mutation in the mouse affecting the cerebellum. Science. 1962 Aug 24;137:610-2
All:  179 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory